ID   A0A417CU03_9FIRM        Unreviewed;       586 AA.
AC   A0A417CU03;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=HAMP domain-containing protein {ECO:0000313|EMBL:RHS99358.1};
GN   ORFNames=DW904_10615 {ECO:0000313|EMBL:RHS99358.1};
OS   Ruminococcus sp. AM42-11.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=2292372 {ECO:0000313|EMBL:RHS99358.1, ECO:0000313|Proteomes:UP000284976};
RN   [1] {ECO:0000313|EMBL:RHS99358.1, ECO:0000313|Proteomes:UP000284976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AM42-11 {ECO:0000313|EMBL:RHS99358.1,
RC   ECO:0000313|Proteomes:UP000284976};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHS99358.1}.
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DR   EMBL; QUIO01000015; RHS99358.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A417CU03; -.
DR   OrthoDB; 138378at2; -.
DR   Proteomes; UP000284976; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000284976};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        289..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          313..365
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
SQ   SEQUENCE   586 AA;  66159 MW;  389BE2831385B67B CRC64;
     MKKKIENLSM QTQLTVVILS VIVLAFGIIL YSGYSGQARS FAEEYTSSTQ TILEMDVANL
     DQYIQGLRIF CVQPCLNVSV YNSLLKRKPL SSSEISDIKQ EIQSSYHSRT DIRSYSITAM
     NQDLCFERNA GVGGQHILST PVKDTEISRP YIACGSNDKY EYLAPPDSED VFFRYYHYLI
     RLRNREPVSL SYVDVDTTQL RLLMKNHQDY GQILCLYNSD GELLYSSSED IRNQEEKEKK
     QLFGLHSDVE NVNIGGISYL ALRRTSEETG IVLLSLLPKS AWDDRARDFL LPLVMQIAVI
     TICLIIIVTL MIRMITIPLK RLSYQMGKMG EGDFSPTAFG GGCKETCALT ESYNDMAAHI
     NELIETNYIS SINEKNSRLQ ALEAQLNPHF LYNTLQAIAT EALLADCQEI YDMIVSLSAN
     LRYTIKGGEL VRLQEELDYV DRYILLQKTR LGGRLEVTKK INPKVNLAVI PKISIQMLVE
     NAIIHGMPEN GAVLHIIIRV CMENNRLLIS VYDDGKGILP EKVKELNDIF SGKSADTGNS
     IGLPNLASRL KILYQGEAGL FLESQGDQFT EVKMELPIRK RENENV
//