ID A0A417HBH4_9FIRM Unreviewed; 624 AA.
AC A0A417HBH4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=NADH-quinone oxidoreductase subunit NuoF {ECO:0000313|EMBL:RHT69163.1};
GN ORFNames=DW741_13130 {ECO:0000313|EMBL:RHT69163.1};
OS Ruminococcaceae bacterium AM28-23LB.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX NCBI_TaxID=2292269 {ECO:0000313|EMBL:RHT69163.1, ECO:0000313|Proteomes:UP000284026};
RN [1] {ECO:0000313|EMBL:RHT69163.1, ECO:0000313|Proteomes:UP000284026}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM28-23LB {ECO:0000313|EMBL:RHT69163.1,
RC ECO:0000313|Proteomes:UP000284026};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHT69163.1}.
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DR EMBL; QUJM01000043; RHT69163.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A417HBH4; -.
DR OrthoDB; 9761899at2; -.
DR Proteomes; UP000284026; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF00037; Fer4; 2.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000284026};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 567..596
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 597..624
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 624 AA; 68044 MW; 5FA9CE0B61767C3F CRC64;
MLKTREELSV LRQTLEGRFA SQVKKILVCA GTGCVAGGSL DIYARLVELL QEKGIHCQVD
LAHEPHGDDV GVKRSGCHGF CEMGPLVRIE PQGWLYIKVK KDDCQEIIEK TILGGEPIER
LCYKMNGEIY KTQEEIPFYK KQTRTVLEHC GHIDATSIQE YIAIGGYKAF EKALFDMDGQ
EIVEEIQKSN LRGRGGGGFP AGRKWAQVRA QEATPKYIVC NGDEGDPGAF MDRSVMEGDP
HRLLEGMMIA GVACGASQGY IYVRAEYPMA VSRLDGAIRQ ARELGLLGEN ILGSGFDFDI
HISRGAGAFV CGEGSALTAS IEGRRGMPRV KPPRTVERGL FDKPTVLNNV ETLANVPHII
TRGADWYRSI GPENSPGTKA FALTGNIQNT GLIEVPMGTT LREIIFDIGG GMRNGAEFKA
VQIGGPSGGC LTKEHLDLPL DFDSLKKVGA MIGSGGLVVM DDKTCMVEVA RFFMNFTQNE
SCGKCVPCRE GTKRMLEILE RIVAGQGKDG DIDLLLELAE TISATALCGL GKTAAQPVVS
TIRYFRDEYE AHVKEKRCPT HNCQKLKRYY IDPQECKGCS KCARMCPVGA ISGEIRSPFT
IDPDKCIKCG ACFGGCSFHA VKEG
//
