ID   A0A417U9W1_9FIRM        Unreviewed;      1413 AA.
AC   A0A417U9W1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=2-hydroxyglutaryl-CoA dehydratase {ECO:0000313|EMBL:RHV50436.1};
GN   ORFNames=DXB46_05800 {ECO:0000313|EMBL:RHV50436.1};
OS   Lachnospiraceae bacterium OM04-12BH.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=2292272 {ECO:0000313|EMBL:RHV50436.1, ECO:0000313|Proteomes:UP000284430};
RN   [1] {ECO:0000313|EMBL:RHV50436.1, ECO:0000313|Proteomes:UP000284430}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OM04-12BH {ECO:0000313|EMBL:RHV50436.1,
RC   ECO:0000313|Proteomes:UP000284430};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHV50436.1}.
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DR   EMBL; QULQ01000004; RHV50436.1; -; Genomic_DNA.
DR   OrthoDB; 9802715at2; -.
DR   Proteomes; UP000284430; Unassembled WGS sequence.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000284430}.
FT   DOMAIN          7..220
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          322..576
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          672..888
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
SQ   SEQUENCE   1413 AA;  157286 MW;  5AABBB70DDBDE4DD CRC64;
     MDHTYTLGID IGSTTVKIAI LDETHQILFS DYKRHFANIR ETLSSLLQDA YQKLGNLTVH
     PVITGSGGLT LANHLKVPFV QEVVAVATSL KEIAPKTDVA IELGGEDAKI IYFEGGNVEQ
     RMNGICAGGT GSFIDQMASL LQTDASGLNE YAKNYQSLYT IAARCGVFAK SDIQPLINEG
     ATKEDLSASI FQAVVNQTIS GLACGKPIRG HVAFLGGPLH FLSELKAAFI RTLKLDEEHT
     IDLDNSHLFA AIGSALNAKE DVSYSMEEMV KKLSSNIKME FEVERMEPLF SSKAEYEAFK
     KRHASHHVET ADLSTYEGNC FLGIDAGSTT TKIALVSEEG KLLYSFYSSN DGSPLKTAIR
     SMKEISKLLP EKAHIVRSCS TGYGEALLKA AFLLDDGEVE TVAHYYAAAF FDPNVDCILD
     IGGQDMKCIK IKNQTVDSVQ LNEACSSGCG SFIETFAKSL NYTVEDFAKT ALFAEHPIDL
     GTRCTVFMNS KVKQAQKEGA SVSDISAGLA YSVIKNALFK VIKVSSADEL GKNIVVQGGT
     FYNDAVLRSF EKIADCEAIR PDIAGIMGAF GAALVARERY TCGQETTMLP MNKILSLQFE
     TSMAKCRGCT NNCRLTINKF SGGRQYISGN RCERGLGKQK NADNMPNLFE YKLKRVFDYE
     PLPADEAKRG NVGIPRVLNM YENYPFWFTF FTRLGYRVIL SPLSTHKIYE LGIESIPSES
     ECYPAKLAHG HVKWLIDQKV DFIFYPALFY ERKEFDEANN HYNCPIVTSY SENIKNNVEE
     IGRGEAILRN PFMSFRDEKT ISDALIKEFK EIPSSEIIEA VHLAWEELAA ARRDMQHKGE
     EVLKWMKETG NRGIVLAGRP YHIDPEINHG IPELINSYHI AVLTEDSISH LAKPERPLIV
     SDQWMYHSRL YAAASYVKTV DNLDLIQLNS FGCGLDAVTT DQVNDILSGS GKIYTCLKID
     EVNNLGAARI RIRSLISAIR VREQKHLERE IHSSAIYKVP FTEEMRKDYT ILCPQMSPIH
     FDVLSAAFKA CGYHFEVLSN DNRHAVDVGL KYVNNDACYP SLMVVGQIMD ALLSGKYDVN
     KVAVIMTQTG GGCRATNYVG FIRRALEKAG MPQVPVISLN MAGIESNPGF HLNLEMLMRA
     AYAAVFGDIF MRCVYRMRPY EKEPGSVEAV HQKWVEKCCA FVSAKHMNFF TFQKMCRQMI
     EEFDAIPITD RKKPRVGIVG EILVKYAPAA NNHLVELLES EGAEAVVPDL LDFMLYCFYN
     QIYKADQLGM SKKTAFISRL GIDGLEYLRS GARKAFEKSV HFEPPCRIYQ TVEYAKEIVS
     IGNQTGEGWF LTGEMIELIH SGVNNIVCTQ PFGCLPNHVV GKGVIKELRK HYPLSNIVAI
     DYDPGASEVN QLNRIKLMLS TAQKNLKAQN QAD
//