ID   A0A417VPA3_9FIRM        Unreviewed;       457 AA.
AC   A0A417VPA3;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=Helix-turn-helix domain-containing protein {ECO:0000313|EMBL:RHV70438.1};
GN   ORFNames=DXB15_06695 {ECO:0000313|EMBL:RHV70438.1};
OS   Roseburia sp. OM02-15.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=2292368 {ECO:0000313|EMBL:RHV70438.1, ECO:0000313|Proteomes:UP000285983};
RN   [1] {ECO:0000313|EMBL:RHV70438.1, ECO:0000313|Proteomes:UP000285983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OM02-15 {ECO:0000313|EMBL:RHV70438.1,
RC   ECO:0000313|Proteomes:UP000285983};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHV70438.1}.
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DR   EMBL; QULX01000005; RHV70438.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A417VPA3; -.
DR   Proteomes; UP000285983; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   PANTHER; PTHR46558:SF4; TRACRIPTIONAL REGULATORY PROTEIN-RELATED; 1.
DR   PANTHER; PTHR46558; TRACRIPTIONAL REGULATORY PROTEIN-RELATED-RELATED; 1.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        152..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          19..73
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50943"
FT   REGION          85..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..113
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   457 AA;  51001 MW;  DE170065633B4C66 CRC64;
     MTGSSFSRRR YLMTLGEKLY TLRTKQNMTQ EQLAEKLQVS RQSISKWESD ATRPDLEKLK
     FLAEFYQVSL DQLLDENMDI FAEESSDLTQ NDDCPPNNQN GTNTSTDFAF TNGSHDATDH
     DHSTASGVSP ETIEKITSEI LKKNHKTWKR TTIGFGTACL ALTVALIVVT VTFSTKLNAL
     STQIAQSSAP VYINNDSDYT TERDTYFQSY NATADSVTED GKNLHVKFTA VLKNYQDNTT
     LTMQLQNNSD QNNIPVTFTC EDGTYTGFAD LPISADTYTT TACIDTNGSK QTVDMNDEYS
     SFSVLSLADW QPSLQADGNS YDKLNRRNDG HFGLSSNNVN CRFFISGVTL EVLANDTKVY
     SYTLDEDDMS LLSEDGTTLY IPYSFTVPKD NTAEDYTVRL HWYNSTLKQY ITYEVSGVGV
     NYFNVSNADV ITSILFNADL DSDDAAPVKV TFSSTEP
//