ID   A0A418KLQ4_9ACTN        Unreviewed;       903 AA.
AC   A0A418KLQ4;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:RIQ18876.1};
GN   ORFNames=DY240_20605 {ECO:0000313|EMBL:RIQ18876.1};
OS   Jiangella rhizosphaerae.
OC   Bacteria; Actinomycetota; Actinomycetes; Jiangellales; Jiangellaceae;
OC   Jiangella.
OX   NCBI_TaxID=2293569 {ECO:0000313|EMBL:RIQ18876.1, ECO:0000313|Proteomes:UP000284057};
RN   [1] {ECO:0000313|EMBL:RIQ18876.1, ECO:0000313|Proteomes:UP000284057}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NEAU-YY265 {ECO:0000313|EMBL:RIQ18876.1,
RC   ECO:0000313|Proteomes:UP000284057};
RA   Han C.;
RT   "Isolation, diversity and antifungal activity of actinobacteria from
RT   wheat.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RIQ18876.1}.
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DR   EMBL; QUAL01000186; RIQ18876.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A418KLQ4; -.
DR   OrthoDB; 9772207at2; -.
DR   Proteomes; UP000284057; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          289..367
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
FT   REGION          848..903
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   903 AA;  98997 MW;  4E56B500B535AF99 CRC64;
     MSRPTDVMSA DEYRPLAMRQ RTLHMVGNSH LDPVWLWPWQ EGYQEARATF WSAIHRMEEY
     PDFVFTCDQV VLLSWVEEQD PELFEQIRKR VAEGRWVMTG GWWVEPDCNM PGGESFVRQG
     LYGQRYLHEK FGVIATVGMN VDPFGHNAML PAILNGQRMD SYTFLRPGPH ESDLDGTAFW
     WEAPDGSRVL AYRIPFEYCS PPGDVAYQTE KSLGQLDRSL GDVMIFYGVG NHGGGPTKAN
     IDSIHRHDQR GSYGRMIMSS PRRYFDELIA RRGPDGLADL PVWRDDLQHH ASGCYSSHSG
     IKQWVRRTQA ALLSAERWAV VGSVTHDDDY PRDELGHAWK QLLFNQFHDI LPGSAIEHAY
     DDARDQLGEA VAIAKRIITR VHNRIARDVA IPFQDGTQPV LVFNPHPWAV TADVELQYGV
     QPTGVHVVDA DGELVPSQPI QSVATTNDKG RGAVVFRAEL PPLGYRLYRL LPGVAPAGLT
     WSGGAAPGSL SASETVLEND VLRAEFDPAT GWLSSLLDKR TGVDLVAGAV GEHTQVSEDP
     TDTWGHGVVS YAWPGEAMKT TRIVLRENGP ERARLRVERS WGRSTLTEEF ILRQGADELE
     VRATIDWREQ AHLLKLRFPV ALADPEATYE IPFGTLRRPV DGAEEPGQSW VDLSAPGAGL
     AVVNNAKHGY DVSPAHDGAS PSIGITAVRS PVYSWHDPRL LDPDGFYSFQ DQGVQRFSYL
     LVPHAGDWRA AGLTRRAAEL GSLPRAMLES FHDGALPAEA SYVVDDGAQV MITAVKGAED
     GDAPAPDLIV RAVETTGVAA AGVRLALPLV DRVVEADFGP HQIRTFRVPR DPRQPIVEVD
     LLEWPVDGDV PAQPVGAGPA SGDGAHGDGR LGSAEPSEGA FTPAERLAAG EGPQHEDGSA
     GGA
//