ID A0A418SHQ7_9RHOB Unreviewed; 308 AA.
AC A0A418SHQ7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=4-hydroxy-tetrahydrodipicolinate synthase {ECO:0000313|EMBL:QPM90493.1};
DE EC=4.3.3.7 {ECO:0000313|EMBL:QPM90493.1};
GN Name=dapA_3 {ECO:0000313|EMBL:QPM90493.1};
GN ORFNames=PSAL_017320 {ECO:0000313|EMBL:QPM90493.1};
OS Pseudooceanicola algae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Pseudooceanicola.
OX NCBI_TaxID=1537215 {ECO:0000313|EMBL:QPM90493.1, ECO:0000313|Proteomes:UP000283786};
RN [1] {ECO:0000313|EMBL:QPM90493.1, ECO:0000313|Proteomes:UP000283786}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lw-13e {ECO:0000313|EMBL:QPM90493.1,
RC ECO:0000313|Proteomes:UP000283786};
RA Poehlein A., Wolter L., Daniel R., Brinkhoff T.;
RT "Genome sequence of Rhodobacteraceae bacterium Lw-13e.";
RL Submitted (AUG-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; CP060436; QPM90493.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A418SHQ7; -.
DR KEGG; palw:PSAL_017320; -.
DR OrthoDB; 9782828at2; -.
DR Proteomes; UP000283786; Chromosome.
DR GO; GO:0008840; F:4-hydroxy-tetrahydrodipicolinate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF67; BLR3884 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000283786}.
FT ACT_SITE 141
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 171
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 49
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
FT BINDING 216
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 308 AA; 32844 MW; 0833F466C639A370 CRC64;
MTKAIRGIYA AAISPFNADG SLDHARLVRY CQHLMSEGGC DGVAPTGTTG EGTSVGLDDR
LALPGHFAAA GIAPERVIFG TGAPSARDCQ MLTLSCVEAG YTNVLVLPPY YYKSPSDDGV
FAYYADLIER VGRDDLRIYL YHFPQMSQVP LSTDLVNRLR AAYGPVIAGL KDSSGDFEQS
RAFIEATGGV AEDFDVYPSS EAFLWQGLDI GSAGIISGST NIFANYVQAA LKAPAGAERD
AAMEQVRRAR ATAGKYPMMA AMKTAEAWRS GDDAWLRMAP PLRPLAPEIA KAFRADLAAL
EPAAETVS
//
