ID   A0A418UV22_9ACTO        Unreviewed;       404 AA.
AC   A0A418UV22;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=AI-2E family transporter {ECO:0000313|EMBL:RJF43827.1};
GN   ORFNames=D4740_02335 {ECO:0000313|EMBL:RJF43827.1};
OS   Actinomyces sp. 2119.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Actinomyces.
OX   NCBI_TaxID=2321393 {ECO:0000313|EMBL:RJF43827.1, ECO:0000313|Proteomes:UP000284680};
RN   [1] {ECO:0000313|EMBL:RJF43827.1, ECO:0000313|Proteomes:UP000284680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2119 {ECO:0000313|EMBL:RJF43827.1,
RC   ECO:0000313|Proteomes:UP000284680};
RA   Li J.;
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC       family. {ECO:0000256|ARBA:ARBA00009773}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RJF43827.1}.
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DR   EMBL; QYRR01000002; RJF43827.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A418UV22; -.
DR   Proteomes; UP000284680; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002549; AI-2E-like.
DR   Pfam; PF01594; AI-2E_transport; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000284680};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        45..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        69..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        95..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        231..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        270..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        296..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          380..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   404 AA;  42828 MW;  99706C8829E19152 CRC64;
     MTAVSSVSAG SSDTSGSSDT LVPSVSRVQD GASDTTRPTR SQGEVIVVTV AALVVAAVGL
     YMVRSLVAPA FFALTLVVTI RPLVSWAARH HVPRGIAAVG AIAILYAFVL SLFAALGVAV
     AQLVDTLPGY SSRFQQIWAD IERMLTSMGV DQASLLDQAT SALDTSRVVS LAQTLLEQLT
     SAGSMMMIMA LVIVFLMFDT MRIEGRVRAL TEFKPEIASA MTGFAASVRS YWLVSTTFGL
     IVAVLDVFAL WALNVPMAVT WGVVSFITNY IPNIGFVVGV IPPALLALVD SGPWTALWVV
     VAYSVLNFVI QTLIQPKFTG DAVGLNTTTT FVSLMFWSTV IGGLGTILAV PLTLFAKALL
     IDSDPRSRWV GIFLTAGDQP LKEQEPEAPD ALGGPGKGPE RLRS
//