ID   A0A418VJG4_9DEIO        Unreviewed;       817 AA.
AC   A0A418VJG4;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=D3875_00200 {ECO:0000313|EMBL:RJF76171.1};
OS   Deinococcus cavernae.
OC   Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=2320857 {ECO:0000313|EMBL:RJF76171.1, ECO:0000313|Proteomes:UP000286287};
RN   [1] {ECO:0000313|EMBL:RJF76171.1, ECO:0000313|Proteomes:UP000286287}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K2S05-167 {ECO:0000313|EMBL:RJF76171.1,
RC   ECO:0000313|Proteomes:UP000286287};
RA   Zhu H.;
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RJF76171.1}.
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DR   EMBL; QYUJ01000001; RJF76171.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A418VJG4; -.
DR   Proteomes; UP000286287; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   CDD; cd17932; DEXQc_UvrD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF13245; AAA_19; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000286287}.
FT   DOMAIN          212..507
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         233..240
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   817 AA;  91877 MW;  77A6D0CCA0CA7593 CRC64;
     MDADLRRRLR QADLLTALRI LQAVDVARHR RDDFTATIQP VQEGSRMSNW LLDAEERFAG
     VRAMADELIR RLGELGPGET LEFNAADLDA QYEAELGGLD ALEALYAVQF LGLANVARGE
     SEVGGVFYLR RGEQRRYGKA AYRPLEVHYG ERARRLHVIR HILSHEKEED RIDLFRWYFT
     ISLEQFCKRF LPNPEAATSP QIPEFRERIL GGLSETQLKV VTDDESRAIL VLAGPGSGKT
     RTIVHRVANL VALRDVNPER VLVLAYNRTA VAEVRERLAA LIGASGIHVD VLTFHGLARK
     LTGLTEKNAP AGMQGDDRFN WLIQQAVDHL RDNPAPYQYV LVDEYQDIKG AEYDLVTLLA
     SFDREGAPTG EEEDDREQPG YLVAVGDDDQ NLYAFMGAKI EFIQRFRDDY DITDEKVVAL
     LPNYRSRPRI VQAANAFIEA SLPARARLKG PDQRVYSVRD GEGQVYIGKY QQRYHAALGI
     AQRAAQLIAQ GTPAEEIAIL ARNWDHLNEV QHALHEAGVA YQMYNVHDQL RPANSYVGGA
     VRDVLTEEPE LAVENARETL ERIRQQLSLS DQDRGWQAIL SATADLHNTI QGALALRINS
     AKPLARRGVV LSTFHSAKGS EFDHVFILSE GMREHGRTPP EDETRALYVA LTRARESVTL
     LRREGDCHPT LLQPGYQHAL KDIGVEVMSL PTGTPLPSEI RYQLFPDPSD LYISAPDVLF
     PAGREAVLRY ARNWDSLQLR NLQLRSPHGA VGRLSRNGRI MLKLKHALER GQVTATGATV
     LRCERDDEWY TRAGYTGLET HHYVVLPQFE VIALLEG
//