ID   A0A418WGD1_9PROT        Unreviewed;       999 AA.
AC   A0A418WGD1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:RJF88959.1};
GN   ORFNames=D3874_19890 {ECO:0000313|EMBL:RJF88959.1};
OS   Oleomonas cavernae.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Oleomonas.
OX   NCBI_TaxID=2320859 {ECO:0000313|EMBL:RJF88959.1, ECO:0000313|Proteomes:UP000284605};
RN   [1] {ECO:0000313|EMBL:RJF88959.1, ECO:0000313|Proteomes:UP000284605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K1W22B-8 {ECO:0000313|EMBL:RJF88959.1,
RC   ECO:0000313|Proteomes:UP000284605};
RA   Zhu H.;
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RJF88959.1}.
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DR   EMBL; QYUK01000011; RJF88959.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A418WGD1; -.
DR   OrthoDB; 5287468at2; -.
DR   Proteomes; UP000284605; Unassembled WGS sequence.
DR   GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR   Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR042204; 2Fe-2S-bd_N.
DR   InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR006277; Sarcosine_oxidase_asu.
DR   InterPro; IPR041117; SoxA_A3.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   NCBIfam; TIGR01372; soxA; 1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF13510; Fer2_4; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF17806; SO_alpha_A3; 1.
DR   PIRSF; PIRSF037980; SoxA; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000284605}.
FT   DOMAIN          171..434
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          518..600
FT                   /note="SoxA A3"
FT                   /evidence="ECO:0000259|Pfam:PF17806"
FT   DOMAIN          616..881
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          906..991
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   999 AA;  106696 MW;  75BC265B5EFEDEE3 CRC64;
     MSAFRLGGGG RIDRTKPINF SFDGKAYQGY AGDTLASALI ANGVHLIGRS FKYHRPRGIM
     SAGSDEANAL VGVGRDQAHY TPNLRATQVE LYEGLVAESQ NRWPSLAFDA GAVNDLLSPF
     FPSGFYYKTF MWPAGAWKRL YEPKIRAMAG LGKAPTAADA DRYTQRYAHA DVLIVGSGPA
     GLAAALAASD SGARVMLCDE QAEFGGSLLG DDQSSIDGKP AAQWLADVLA TLAARENVTL
     LSRTTAFGFY GHNFLGLAER VTDHLAKADP RLPRERLWQV RARQVVFAAG AIERPLVFPE
     NDRPGVMLAD AARLYATRYG AKPGRRAVIA TAADEAYRAA LALHAVGVEI AAIVDLRPKV
     EGPLPDAARA AGLKILTGHV VVGTRGRLRV SSVDIAPVSG DTVGKSSRLA CDLVAMSGGF
     TPSLHLFSQS RGKLKYDPLT QSYLPGTSAA AERSAGACRG IFSLSSVLAD GHAAGSEAAQ
     KAGFAPKGLR SFAASALDAG AGGFVGAVPH ARNPATVKAF VDFQNDVTAK DIKLATREGF
     KSIEHIKRYT TTGMATDQGK TSNMNALGIV SKALDKPIPE IGLTTFRPPY TPTTFGTFAG
     LSRGDLFDPV RTTPIHDWAV EQGAVFEDVA LWKRARFFPR GGEDMHAAVN RECVAVRAGV
     GIFDATTLGK IEVVGPDAAE FMNRMYTNAW LKLEVGRCRY GAMLREDGFV LDDGVVGRMA
     TDRFHVTTTT GGAPRVLNMM EDYLQTEWPD LNVWLTSTTE EWAVIALQGP NARKVIEPLV
     EGIDLSPAAM PHMSVREGRI LGVPTRLFRV SFTGELGFEI NVPASYGRAV WEAVYEAGKA
     HGITPYGTET MHVLRAEKGY IIIGQETDGT AGPDDVGLGW AVGKTKKDFV GKRSLARPEM
     SNPNRKQLVG LLSLDDKAVL EEGAQIVADP AQAIPMTMIG HVTSSYWSAA LGHPIALAMV
     AGGRARMGEV LHVPMPGGTI AVKVTEPVFY DPKGVRLDG
//