ID   A0A418WKR5_9SPHN        Unreviewed;       335 AA.
AC   A0A418WKR5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:RJF90608.1};
GN   ORFNames=D3876_10315 {ECO:0000313|EMBL:RJF90608.1};
OS   Sphingomonas cavernae.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=2320861 {ECO:0000313|EMBL:RJF90608.1, ECO:0000313|Proteomes:UP000286100};
RN   [1] {ECO:0000313|EMBL:RJF90608.1, ECO:0000313|Proteomes:UP000286100}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K2R01-6 {ECO:0000313|EMBL:RJF90608.1,
RC   ECO:0000313|Proteomes:UP000286100};
RA   Zhu H.;
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RJF90608.1}.
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DR   EMBL; QYUM01000003; RJF90608.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A418WKR5; -.
DR   OrthoDB; 9809185at2; -.
DR   Proteomes; UP000286100; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43401:SF5; ALCOHOL DEHYDROGENASE-RELATED; 1.
DR   PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286100};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          25..127
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          169..291
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   335 AA;  34717 MW;  AADC3E810C4D9C3F CRC64;
     MRAIVYPGAG APLVLERIPD PVPGPGELVI KVHRCGICGT DLHMTEGSGF EFPAGTVPGH
     EYAGEVVAVG KEVTGWAEGD RLTALPSTGC GKCAACAQGN LVLCRDAPGV MGGFAEYLKV
     PASVAVKLPS VLSLADGALI EPMAVGLYGM RQVPMDACSR VLVLGGGSVA LAAIWWARRL
     GAGRIVAASR SPRRAEMALA MGADAFVAFG ENEAAEIREA LGGPPDTVVE CVGTSGFLGK
     AVQHVASLGQ VLSMGFCTVP DTLIPAIAAT KGVTMRFPVG YALSDFERVA RDIDSCHADP
     KMMISSVVSL DEVPATFDRL RAPNAETKVH ITFDS
//