ID A0A418XRK7_9BURK Unreviewed; 1426 AA.
AC A0A418XRK7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=D3872_14720 {ECO:0000313|EMBL:RJG15130.1};
OS Massilia cavernae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Telluria group; Massilia.
OX NCBI_TaxID=2320864 {ECO:0000313|EMBL:RJG15130.1, ECO:0000313|Proteomes:UP000284006};
RN [1] {ECO:0000313|EMBL:RJG15130.1, ECO:0000313|Proteomes:UP000284006}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K1S02-61 {ECO:0000313|EMBL:RJG15130.1,
RC ECO:0000313|Proteomes:UP000284006};
RA Zhu H.;
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJG15130.1}.
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DR EMBL; QYUP01000120; RJG15130.1; -; Genomic_DNA.
DR OrthoDB; 5477914at2; -.
DR Proteomes; UP000284006; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00063; FN3; 1.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011110; Reg_prop.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR011123; Y_Y_Y.
DR PANTHER; PTHR45339:SF3; HISTIDINE KINASE; 1.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF01627; Hpt; 1.
DR Pfam; PF07494; Reg_prop; 7.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF07495; Y_Y_Y; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 4.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50894; HPT; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:RJG15130.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000284006};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:RJG15130.1}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1426
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019325701"
FT DOMAIN 929..1152
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1172..1294
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 1335..1426
FT /note="HPt"
FT /evidence="ECO:0000259|PROSITE:PS50894"
FT COILED 825..922
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 1221
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 1374
FT /note="Phosphohistidine"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00110"
SQ SEQUENCE 1426 AA; 155301 MW; 86F7F4A8BFC2F519 CRC64;
MTFLIRWLAA LALLAALAPG AGAAAPARTL RFEHLSVEHG LAQESVLAIV QDRDGFMWFG
SQAGLSRFDG YRVVVYRHDV NNRKSLANNW VKVLHVDARG ELWVGTDGGV DRFDPATQSF
VHYLPQETVR RGNGNRHIRA IADDGEGGLW IGTADGLQHL DPASGKFTVW NHVPDDPGSL
SDNQINALAV DAGGRLWVGT AAGLDSLASG ARVFEHHHAR DGDMRFNTVQ ALLVDSQQTL
WVGSTGGLER SSGDVRKAGA ALRRQRLGDA VGIRHEVIAT LYEDADGTIW VGTYSEGLYR
WDGRAQRFQA HRHVVTDAHS VADNRISALF RDRVGILWVG TWSAGVSRVD LNSGGFARIV
RQPDAPTTLT GNNVRAILDD GRGKVWIGTN SGLNLYDPAS GAVRAWRHEP RNPNSLADPV
AGALAHDRSG ALWVGGDHGV TRFDQDSGRF TRVQLGDADG NKVRGMMLDR SGMLWIASRG
GLHRLDPATL KVASYRHDTA DDSSLADNAV RPMLEDSRGR LWIGTFDGLD LMDRARGTFR
HFRHDPNKTG SLSHDEVHYL LEDSKGTVWV GTAGGLNRMN IDARGEVSFR RYTVGDGMAD
DAIAAILEDS AGYLWMSTNT GISRFDPGTG KWRNYSSVDG ITEGAFFDGS AVRATDGTLY
FGGFNGVTAF NPRAISDNRI PPRAIVTGFQ IFNQPVEAAR PGLVRGPVER MREIALAASD
SVFSLEFSGL HYAAPQRNRF AYQLEGFDRG WVDTEAGKRF ATYTNLDPGT YTFRVKAANK
DGVWGVPSDP LVITIAPPVW KTWWFRSLAA ALVLGSAWFA YRLRLSGLRR QKSLLERQVR
ARTEEIEQQN RRLEQQKREL EAQRFEAERQ RAEAERRRAD AERQKAEVVR QKENVERAHR
DISVLSERLS FAKRKAEDAT RQKSEFLADM SHEMRTPLAG VIGMLGFALR DARLAPATRE
QVARGQANAQ SLLGIVNDLL DFSKIEAGKL AIENIDFSLA AKIESVVSLF EEQAAAHSVD
FGIELDDDLP RFVVGDPTRL RQVLVNLVGN AFKFTNEGKV TLRVARSAGA SDGVNLIRFS
VTDTGIGIAP DALARLFQKF EQADSTTTRR YGGTGLGLAI CRQLVQLMGG EITAESTEGV
GSTFSFVLPL ADGSMPAPLP HVLREPHSHR LNVLCAEDFP TNQIIVRAML EDLGHRATVV
GNGLLAVEAC ARAGYDLVLM DGRMPEMDGA RATQMIRAGG PVGAPVRDPK VMIVALTANA
SDEDRARYLG AGMDDFLTKP IDEGALHALL GRAVARRLAE GAQLEPMPGR APTTSELDAM
FGVVTGPAGT GPSQDADLFE RIRAAFAADV PARRAELEQA VASCDHEAAA RLLHGMKGSA
AHLGAGALHA LCSELEAAAD ARRWDALADA LPRLYRLLDG FDTEAA
//
