ID A0A418ZZL0_9RHOB Unreviewed; 679 AA.
AC A0A418ZZL0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=D3P06_04970 {ECO:0000313|EMBL:RJL06015.1};
OS Paracoccus aestuarii.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=453842 {ECO:0000313|EMBL:RJL06015.1, ECO:0000313|Proteomes:UP000285530};
RN [1] {ECO:0000313|EMBL:RJL06015.1, ECO:0000313|Proteomes:UP000285530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19484 {ECO:0000313|EMBL:RJL06015.1,
RC ECO:0000313|Proteomes:UP000285530};
RA Jurado V., Gutierrez-Patricio S., Gonzalez-Pimentel J.L., Laiz L.,
RA Saiz-Jimenez C.;
RT "Paracoccus onubensis nov. sp. a moderate halophilic bacterium isolated
RT from Gruta de las Maravillas (Aracena, Spain).";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJL06015.1}.
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DR EMBL; QZEV01000014; RJL06015.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A418ZZL0; -.
DR OrthoDB; 9806690at2; -.
DR Proteomes; UP000285530; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF3; ATP-DEPENDENT HELICASE_DEOXYRIBONUCLEASE SUBUNIT B; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000285530}.
FT DOMAIN 7..304
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 305..564
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 34..41
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 679 AA; 74251 MW; C909EA249107451B CRC64;
MATAYLDKLN EQQRAAVVFG TDGPDLPPPL LVIAGAGSGK TAMLAHRVAH LLVGGADPRR
ILLMTFSRRA ASELTRRVER ITAAATGSPV AAEALIWSGT FHAVGARLLR EHALAIGLHP
DFSIHDREDS ADLMNLARHG LGLSKTESRF PTKGTCLAIY SRTVNSGAPL AEVLREHFPW
CAGSEAQLKQ LFGAYVAAKQ AQNVLDYDDL LLAWAQVMTA PDFAAHIGAT WDHVLIDEYQ
DTNRLQARIL TALKPDGRGL TVVGDDAQSI YAFRAADVRN ILDFPDSFTH RAAVIALERN
YRSTQPILAA ANAVIAAASE RHAKELWSDR AGVEKPRLVT VGTEALQARY MVDRILADRE
AGMRLKDQAV LFRTSSHAAQ IEAELTRRNV PYVKFGGLKF LDSAHVKDLL SVLRLKRNPR
DRVAGFRVLQ LIPGVGPTAA GRILDALDLA TDPRAAWGDV APPPRADASW TDFVAAMTTE
APWPAAIGLA RGWYDPHLDR IHEDAEARRA DLLQLEQIAA GYLSAEAFLT ELTLDPPDAT
SDQAGVPLKD EDYLILSTIH SAKGQEWRSV HILNAVDGCI PSDLGTGSTH ELEEERRLLY
VAMTRAKDQL TLGLPLRFYV TQQTRNGDRH VYAMRTRFIP SAILDRFEAV NWSPAPVASE
ARPAPAPIDI AANMRAMWG
//
