ID A0A419A4C6_9RHOB Unreviewed; 1765 AA.
AC A0A419A4C6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:RJL09155.1};
GN ORFNames=D3P05_15290 {ECO:0000313|EMBL:RJL09155.1};
OS Paracoccus siganidrum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=1276757 {ECO:0000313|EMBL:RJL09155.1, ECO:0000313|Proteomes:UP000283587};
RN [1] {ECO:0000313|Proteomes:UP000283587}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26381 {ECO:0000313|Proteomes:UP000283587};
RA Jurado V., Gutierrez-Patricio S., Gonzalez-Pimentel J.L., Miller A.Z.,
RA Laiz L., Saiz-Jimenez C.;
RT "Paracoccus onubensis nov. sp. a moderate halophilic bacterium isolated
RT from Gruta de las Maravillas (Aracena, Spain).";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJL09155.1}.
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DR EMBL; QZEW01000068; RJL09155.1; -; Genomic_DNA.
DR Proteomes; UP000283587; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01720; NRPS-para261; 1.
DR PANTHER; PTHR45398; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR PANTHER; PTHR45398:SF1; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000283587}.
FT DOMAIN 1420..1495
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1765 AA; 190241 MW; 8B078EDB999FCE4B CRC64;
MRWLQDQPGN HDGFHQAMLL RVPAHAPQVF EQALDDMLAL HHALRLRGEG ETMAIAPQGS
IRARDCLAVL APGEDPTAAA ERALAELSPR KGQMLRAVLA PDPDRPDARL LWLAIHHLAI
DGVSWRILLP DLAAAAEARA KGREPGLDPV PVSWRDWATA LPGAAAARRH ELPFWQRMTP
DAAWPAGPLD PERDTTETRG GLMRELPADI TRCLLTRAPQ RIGGGVGDVL LAGFAIALAG
WQAERGLDPA TAAFELEGHG REPLAEGADL SRSIGWFTSQ FPLRLSLPDA TVPADDEALD
RLMKSVKDQL ARLPANGLGY GLLRHLDPEG KAALAGHPAA WAGFNYLGRF EAATDAATDA
ADGGFWRPAE GAFAAPRPPR PRPLARLVDL NAVTEDRPGG PVLVADWSWA ARHLDQAEIA
ELAGRWFDAL ARIAALTEAR PERVLTASDV ALSGLDQPAI DALSARLPLA DILPLSPLQQ
GFLFHDSYDD QGAGAYVVQM VFALDGPLDP QRLRRAMRAL LARHPNLAAR FDLVGERMVQ
LIPRQPDLPW LTHDLSGDHT QRHDEQNAIL KADQNTRFDL RNDPPIRVTL ISETKNKHKI
AITTHHIAID GWSNPIMLQE LMALYDDPGA FDGRPAPQYR DYLAKIMETD EGTSITAWRD
HLAGLEAPTR IAPEAGSIPR PELCDRIIAA GDWQRLADAA QAAGVTQNTL AQQAWAMVLS
HLTGQTDVTF GTIVSGRPPE IAGIEDMVGL FINTVPTRVR LRPGETQSAL SQRLQREQTA
LTGHHHVALP RLTQEMRMGE LFDTLLVYEN YPVRAAAGQE DAPQEALQVS AAGSHGAAAT
HYPLGMMIVP ARPGEAAKLT LSYRADLFDA AYAERVQTLF ARALMLLADA PDLPVAEIGL
EDAPHVSKGS ARRDPRMVTD LFAQQVARNP DAVALGWENG LMSYAQLDRD SDRLAGHLIR
LGVRPGEIVG ISLPRGPEVA IAVLGLWKAG AAYLPLDPAY PDARLEHMLT DARPRLVVTD
PRTRQMLPAG DWSAVMVQGP HLVGADQDAP PPRPRLIADS PAFVLYTSGS TGAPKGVVGT
HGTVAERLCL PLPEAGDAGA RVYIHKTTLN FIDAIHELFV PLLHGDRVEI APHDDLGDVE
GIARVIETRG VSRIVLVPSL LRALLDLPGA AKRLQGLHLC VSSGEALPGE LAVRFHRLLP
HARLLNIYGT SEMWDASAAE AGRDQDMASG VPIGQALDGV GTAVLDGFLR PVATGVAGEL
YVSGHGVAQG YLNRPDLTAE RFLACPEGSG QRMYRTGDLV RRRANGGLDY LGRADQQIKI
RGFRIEVDEI VALLMKQPGI RQAIAAAIPS PRGGSDLIAY VVATDGATPD PRALRQALAA
QLPRNMVPSA VMVVDGLPLL PNGKVDRAAL PRPEARPSRP AQTELQARLC AAMAEVLSLP
EIGIDDDFFE MGGHSLLAAR LAARLRMVTG RTVGVRAIFE APTVQQLELR LSQGEDSFSD
APVLDFPPVG LCAGPAPEPL FCLHPAGGIG WWYRSLPAQL GRGRTVHALQ GPEFCGTGSP
ATMEDAAAEY LDRIETIRPN GPLHLLGWSY GGALAFEIAL QAQARGRQVA TLALMDAFLL
ADLPGFDPAA NDKSAGQVLA DLLAVTGRLT AEIDRETPDY QRAAQALHGT ILGGLDAAML
ERFVQASRAD VARLGHYRPA GRFDGRLVYF DAVGDRQEPD GSGSEMFARH ASDLTRHPVA
CRHDEMGHPQ HLAAIGRLLS TEYGL
//
