ID   A0A419HCR9_9PSEU        Unreviewed;       626 AA.
AC   A0A419HCR9;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=2-oxoacid:acceptor oxidoreductase subunit alpha {ECO:0000313|EMBL:RJQ68865.1};
GN   ORFNames=D5S17_31590 {ECO:0000313|EMBL:RJQ68865.1};
OS   Pseudonocardiaceae bacterium YIM PH 21723.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae.
OX   NCBI_TaxID=2340915 {ECO:0000313|EMBL:RJQ68865.1, ECO:0000313|Proteomes:UP000285726};
RN   [1] {ECO:0000313|Proteomes:UP000285726}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIM PH 21723 {ECO:0000313|Proteomes:UP000285726};
RA   Miao C.;
RT   "YIM PH21274 draft genome.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RJQ68865.1}.
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DR   EMBL; QZFT01000082; RJQ68865.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A419HCR9; -.
DR   OrthoDB; 9794954at2; -.
DR   Proteomes; UP000285726; Unassembled WGS sequence.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR   GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   InterPro; IPR022367; 2-oxoacid/accept_OxRdtase_asu.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   NCBIfam; TIGR03710; OAFO_sf; 1.
DR   PANTHER; PTHR32154:SF20; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORA; 1.
DR   PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF01558; POR; 1.
DR   Pfam; PF01855; POR_N; 1.
DR   SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000285726}.
FT   DOMAIN          30..218
FT                   /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01558"
FT   DOMAIN          267..482
FT                   /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT                   pyrimidine binding"
FT                   /evidence="ECO:0000259|Pfam:PF01855"
SQ   SEQUENCE   626 AA;  67403 MW;  14CE9AD4BFAC8E67 CRC64;
     MSLDVGSAPH RDTEVRKLDR VVIRFAGDSG DGMQLTGDRF TSETALFGND LSTLPNFPAE
     IRAPAGTLPG VSSFQLHFAD YDILTPGDRP DVLVVMNPAA LKANIGDLPH GAILIINTDE
     FSKRALQKVG YETDPLEDGS LEPYQLHKIA MATITRAALE ETGLSKKDAE RAKNMFALGL
     LSWMYHRPTE GTERFLREKF AKKPDIAEAN VLAFRTGFNY GETTESFAVT YEVAPAKLDQ
     GTYRQITGNT ALAYGVVAAG QLSKLPVFLG TYPITPASDI LHELSKHKNF NVTTFQAEDE
     ISAVGAALGA SFGGSLGVTT TSGPGIALKS ETIGLAVMTE LPLLVIGVQR GGPSTGLPTK
     TEQADLLQAM FGRNGEAPVP IVAPQSPSDC FDAAVEATRI ALKYRTPVIL LSDGYIANGS
     EPWMVPDVAQ LPDISVRFAT EPNAPDGSGE FWPYLRDPET LARAWAVPGT PGLAHRIGGL
     EKADGKGGIS YDPDNHDKMV RLRQAKIDGI DVPDIEVEDP SGEARVLVLG WGSSFGPIRA
     GCRRVRGKGH NIAQAHLRHL NPFPKNLGEV LRKYDKVVIP EMNLGQLALL VRARYLVDAI
     SYTKVAGLPF KAEELQDALT EIVKGV
//