ID A0A419HME2_9PSEU Unreviewed; 521 AA.
AC A0A419HME2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=NADH-quinone oxidoreductase subunit M {ECO:0000313|EMBL:RJQ77273.1};
DE EC=1.6.5.11 {ECO:0000313|EMBL:RJQ77273.1};
GN ORFNames=D5S17_16370 {ECO:0000313|EMBL:RJQ77273.1};
OS Pseudonocardiaceae bacterium YIM PH 21723.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae.
OX NCBI_TaxID=2340915 {ECO:0000313|EMBL:RJQ77273.1, ECO:0000313|Proteomes:UP000285726};
RN [1] {ECO:0000313|Proteomes:UP000285726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM PH 21723 {ECO:0000313|Proteomes:UP000285726};
RA Miao C.;
RT "YIM PH21274 draft genome.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00009025}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJQ77273.1}.
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DR EMBL; QZFT01000036; RJQ77273.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A419HME2; -.
DR OrthoDB; 9768329at2; -.
DR Proteomes; UP000285726; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR NCBIfam; TIGR01972; NDH_I_M; 1.
DR PANTHER; PTHR43507:SF1; NAD(P)H-QUINONE OXIDOREDUCTASE CHAIN 4, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:RJQ77273.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000285726};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 475..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..427
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 521 AA; 55345 MW; 2CE044E28DC75188 CRC64;
MGAASLLIAM LLPLVGAIVV AQFSKNEKTA KTVAMAFALA ELIPAAIAWV EYDPNGDRLQ
LTMVADWIPA LGVHFALGVD GIALVMLALI AVLVPIVLLG DWVGRLPAGR SYAGYAALIL
LMEMCMVGVF VAIDVFLFYV LFEVMLIPMY FLIGRFGGPR GSYAAVKFFL YSLFGGLIML
GSVIGCYVVA QNRTGTGTFM WADLVGALHG ASTTTQIWLF LGFFLAFAIK APLVPLHTWL
PDATAEAPIG AGVLLVGVLD KVGTFGFLRY NLALFPQASQ KLAPYVLVLA VAGVLYGSLL
AVGQRDMKRF MAYVSIAHFG FIALGIFAFT SQALAGAVLY MVMHGFSTGM LFVCAGMVID
RGGSRNIEDY GGMHRATPLL GGLFLIAGLS VLSLPGTNSF VPEFLVLVGS FPREPVFTVL
ATIGMVLAAL YVLWMYQRIF QGPLRGTALV GLAGGPGTAQ DPVTSKIRDL NVREMLVLAP
LVIAVVGFGL YPKPVLDVIG PSVSATMHEV GLTDLVEGGN R
//
