ID   A0A419SBX5_9SPHI        Unreviewed;       821 AA.
AC   A0A419SBX5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   22-FEB-2023, entry version 7.
DE   SubName: Full=Zinc-dependent metalloprotease {ECO:0000313|EMBL:RKD20297.1};
GN   ORFNames=BCY91_01375 {ECO:0000313|EMBL:RKD20297.1};
OS   Pelobium manganitolerans.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pelobium.
OX   NCBI_TaxID=1842495 {ECO:0000313|EMBL:RKD20297.1, ECO:0000313|Proteomes:UP000283433};
RN   [1] {ECO:0000313|EMBL:RKD20297.1, ECO:0000313|Proteomes:UP000283433}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YS-25 {ECO:0000313|EMBL:RKD20297.1,
RC   ECO:0000313|Proteomes:UP000283433};
RA   Wu S., Wang G.;
RT   "Genome of Pelobium manganitolerans.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RKD20297.1}.
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DR   EMBL; MBTA01000001; RKD20297.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A419SBX5; -.
DR   OrthoDB; 9776599at2; -.
DR   Proteomes; UP000283433; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd04276; ZnMc_MMP_like_2; 1.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   InterPro; IPR033413; DUF5117.
DR   InterPro; IPR033428; DUF5118.
DR   InterPro; IPR032534; EcxA_zinc-bd.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR034032; Zn_MMP-like_bac.
DR   PANTHER; PTHR38478; PEPTIDASE M1A AND M12B; 1.
DR   PANTHER; PTHR38478:SF1; ZINC DEPENDENT METALLOPROTEASE DOMAIN LIPOPROTEIN; 1.
DR   Pfam; PF16313; DUF4953; 1.
DR   Pfam; PF17148; DUF5117; 1.
DR   Pfam; PF17162; DUF5118; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:RKD20297.1};
KW   Metalloprotease {ECO:0000313|EMBL:RKD20297.1};
KW   Protease {ECO:0000313|EMBL:RKD20297.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000283433}.
FT   DOMAIN          49..97
FT                   /note="DUF5118"
FT                   /evidence="ECO:0000259|Pfam:PF17162"
FT   DOMAIN          106..293
FT                   /note="DUF5117"
FT                   /evidence="ECO:0000259|Pfam:PF17148"
FT   DOMAIN          425..731
FT                   /note="EcxA zinc-binding"
FT                   /evidence="ECO:0000259|Pfam:PF16313"
SQ   SEQUENCE   821 AA;  92801 MW;  523E162F60CF1C59 CRC64;
     MHKNIYKLGI ITFIGVSTSL SGCFLKKKKP APTPVVNKPV ATQKPGALKP YRDIISAKAK
     TDSGLFAVHK VDEKYFYEIA DTLFGREMLA VTRYVKTPAV DGVYGGEEIN EQVWVWEKRD
     KQVLLRVQSY ANVAADSSEM FQSVRNSNLA PILAVFDIKS LGKDSNGVVI DVSDFFSKDI
     NAIGLSPDTR TAYKITRLDE SRSYIDTIKS FPINIETRTV KTYLANNPPV DNSLGSVTVE
     LNTSMVLLPK VPMQARLYDQ RVGYFSRRQT DYGIDAQKAT VTRYVARWRL EPKDSAAYAR
     GELVEPKKKI VYYIDPATPK KWRPYLIEGV KDWNAAFEAA GFKNAITCLE APTDDPDWSP
     EDARYSVIRY FASNIANAYG PHISDPRSGE IIESDIGWYH NVMNLVRNWF FVQTAAVNPE
     ARMPKFKDEV MGQLIRFVSS HEIGHTLGLA HNFGSSVAYP VDSLRSASFT QRMGGTAPSI
     MDYARFNYIA QPQDQGVLLY PGIGPYDKWA IKWGYTYFPG KNMDEETVVL NKWTVARAGN
     PLYFYGRQTS NPIDPRSQSE DLGDDAMKAS AYGIQNLKRI LPNIEKWTYE EGKAYENLQE
     LYGEVINQFT RYMGHVKSNI GGIYENFKTY EQSGAVYTPV PKAVQQQAMD FIIKQAFATP
     TWLTATPSVK KFDDATLSTR IGRMQLVTLN SILEFSRLAR VIDNTAKNGN QAYTINQLMS
     DLQNGIFTEL GTGEKIDIYR RNLQRAYIER LRYLLTQDQS NVNEPTRIIV DYSDIRPMTR
     LALTNLQQSI KRALPRYNDA LTKAHLNDAL ARIDLILNPK G
//