ID A0A419SQU1_9BACL Unreviewed; 363 AA.
AC A0A419SQU1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=BEP19_16335 {ECO:0000313|EMBL:RKD26767.1};
OS Ammoniphilus oxalaticus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
OC Aneurinibacillus group; Ammoniphilus.
OX NCBI_TaxID=66863 {ECO:0000313|EMBL:RKD26767.1, ECO:0000313|Proteomes:UP000284219};
RN [1] {ECO:0000313|EMBL:RKD26767.1, ECO:0000313|Proteomes:UP000284219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RAOx-1 {ECO:0000313|EMBL:RKD26767.1,
RC ECO:0000313|Proteomes:UP000284219};
RA Poppleton D.I., Gribaldo S.;
RT "Novel Firmicute Genomes.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKD26767.1}.
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DR EMBL; MCHY01000002; RKD26767.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A419SQU1; -.
DR OrthoDB; 9775794at2; -.
DR Proteomes; UP000284219; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000284219}.
FT DOMAIN 15..350
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 363 AA; 40117 MW; F0B2A241A415155E CRC64;
MNQDLHVIFT VENSVGWITL NRPKALNALS YEMVLEIREQ LRIWKDNPAV ALVCIVGAGD
RALCAGADIR ALYQEKHTSG DARALARAYF SAQYEMDHII HTYPKPCLVI MDGIVMGGGV
GLSIGCSHRL VTENTKWAMP EMNIGFFPDV GASYFLNQMP GHVGRYLALT SETITAADTL
YIGAADLYLA AESVKPCLEA LRAHPWQQDG VQEDLATLLH SLSSPSPEPS LLEEHQDKIN
EHFRHNCVEE IVSSLKEASL VGCDWSAQKI GAIQQKSPTS LKVTLEQMMR GKTLPLDACF
NMEVELGVEF MGRDDFFEGV RATLIDKDKA PQWSPQHLKD VTSEMVAAYF QEMGHTSSSS
SIS
//
