ID A0A419V5B8_9BACL Unreviewed; 381 AA.
AC A0A419V5B8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=ATL39_1924 {ECO:0000313|EMBL:RKD73622.1};
OS Sinobaca qinghaiensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Sporolactobacillaceae; Sinobaca.
OX NCBI_TaxID=342944 {ECO:0000313|EMBL:RKD73622.1, ECO:0000313|Proteomes:UP000285120};
RN [1] {ECO:0000313|EMBL:RKD73622.1, ECO:0000313|Proteomes:UP000285120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17008 {ECO:0000313|EMBL:RKD73622.1,
RC ECO:0000313|Proteomes:UP000285120};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKD73622.1}.
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DR EMBL; RAPK01000008; RKD73622.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A419V5B8; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000285120; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000285120}.
FT DOMAIN 23..363
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 381 AA; 42746 MW; 582718389F9BC3D9 CRC64;
MLKVMTVLGT RPEGIKMAPV IQALNQSTQF ESVFVNTAQH REMLDQVLEL FHIVPDYDLN
IMQNGQSLEQ LTSRIFLGLS PIIEQEKPDL VLVHGDTTTT FIGAYASFLK QVPVAHVEAG
LRTNNMKSPF PEEGNRQLVG RIADYHFSAT AANRENLLQE NVQNEKIAVV GNTVIDALLT
VANKPYTFPE HLEPIFQSGK KTILLTTHRR ENLEELQHVY KAINRLVTEN DDIQIVFPVH
KNPVIRKKVT ETIEDTSRVH LIEPLDYENF VHVMKHSYLV ITDSGGIQEE APALGKPVLV
ARNTTERPEG VEAGTLKLVG TSEDMIYKEA SQLLNDPQAY HEMSQIKNPF GNGESAQAIL
QQIQEWKAPA LNSKQKSESI T
//
