ID A0A419W5G2_9BACT Unreviewed; 588 AA.
AC A0A419W5G2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=CIC family chloride channel protein {ECO:0000313|EMBL:RKD90699.1};
GN ORFNames=BC643_1040 {ECO:0000313|EMBL:RKD90699.1};
OS Mangrovibacterium diazotrophicum.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Prolixibacteraceae;
OC Mangrovibacterium.
OX NCBI_TaxID=1261403 {ECO:0000313|EMBL:RKD90699.1, ECO:0000313|Proteomes:UP000283387};
RN [1] {ECO:0000313|EMBL:RKD90699.1, ECO:0000313|Proteomes:UP000283387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27148 {ECO:0000313|EMBL:RKD90699.1,
RC ECO:0000313|Proteomes:UP000283387};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKD90699.1}.
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DR EMBL; RAPN01000001; RKD90699.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A419W5G2; -.
DR OrthoDB; 9812438at2; -.
DR Proteomes; UP000283387; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000283387};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 464..522
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 588 AA; 64840 MW; 82851423622526E4 CRC64;
MMELKTKLLA FFNRMNDSKK VYWLSLLIGI VCGTAALLLK NLIHLIGETL VGNLKESDEN
YLFLAFPLIG IAITVLIVKL LIKDDLGHGV SKVLGAISLN KGNLKRHHTF SSMITSSFTI
GFGGSVGAEA PVVLTGSAIG SNLARFFNLS HAQTMLMLGC GATGAIAGIF KAPLAGIVFT
LEVLMLDLTM ASLLPLLISG ISAAVLAYYF MGDEVLFKFE LVNSFDAGNI PFYLILGVFS
GFISLYFTRM TMYLERRFKL IRKPINKILI GGLILGLCIF LFPPLWGEGY HSIDKIFNGL
GPDLLDNSLF FNFKDQQWFI VIFLLLLVFI KVIAMTATTA SGGVGGIFAP TLFVGAIGGY
FVASFFNLVL GLNLPIDNFA LAGMGAMMAG VMHAPLLGIF LTAEITGGYQ LFFPLIIAAI
ASYVTIMAFE PYSIYTKALA KKGELVTHHK DKAVLHFMAV RELIETDFAI VSPEATLGDL
TKIIAKSKRN LFPVVDDEGM MKGMIKMDDI REIIFNHELY DKIYVKDLMY MPEHYISPRD
TMLKVAEKFE SSARFNLAVL DNGKYLGFIS RARVFSNYRN FVRTLSHD
//
