ID A0A419WBP3_9BACT Unreviewed; 1049 AA.
AC A0A419WBP3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 13-SEP-2023, entry version 11.
DE SubName: Full=HAE1 family hydrophobic/amphiphilic exporter-1 {ECO:0000313|EMBL:RKD92895.1};
GN ORFNames=BC643_3272 {ECO:0000313|EMBL:RKD92895.1};
OS Mangrovibacterium diazotrophicum.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Prolixibacteraceae;
OC Mangrovibacterium.
OX NCBI_TaxID=1261403 {ECO:0000313|EMBL:RKD92895.1, ECO:0000313|Proteomes:UP000283387};
RN [1] {ECO:0000313|EMBL:RKD92895.1, ECO:0000313|Proteomes:UP000283387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27148 {ECO:0000313|EMBL:RKD92895.1,
RC ECO:0000313|Proteomes:UP000283387};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKD92895.1}.
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DR EMBL; RAPN01000001; RKD92895.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A419WBP3; -.
DR OrthoDB; 9758940at2; -.
DR Proteomes; UP000283387; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042908; P:xenobiotic transport; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004764; MdtF-like.
DR NCBIfam; TIGR00915; 2A0602; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF9; SIMILAR TO MULTIDRUG RESISTANCE PROTEIN MEXB; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000283387};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 338..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..456
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 868..887
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 894..918
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 924..949
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 970..989
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1001..1027
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1049 AA; 114009 MW; 08F1A5BCFE7E6D20 CRC64;
MFRKFIERPV LSTVVSIILV ILGVLGITTL PIEQYPDIAP PTIRVSATYT GADAATVMNS
VIIPLEEQIN GVENMIYMTS SASNTGSATI EVYFKQGTDP DMAAVNVQNR VAQANALLPA
EVTKAGVTTA KRQNNMLLVF SIYSPNGQYD ETFLQNYSKI NVLPQIQRVT GVGEAMVFGA
KDYSMRVWLR PDVMANYNLM PSDVTAAIAA QNLEAAPGRF GQQNDQTFEY VLRYKGKLRE
PSEFENIIIK ADADGNILRL KDVARIEMGA LNYSMTTATM NKPGVAMAIF QAAGSNARDV
IIQCQDVIEE ASKSFPPGVD YQILMNTNDF LDSSIEKVLH TLLEAFILVF IVVFIFLQDF
RATLIPAIAV PVSIIGTFFF LNLFGFTINL LTLFALVLAI GIVVDDAIVV VEAVHAKLDQ
GAKNARTASI SAMSEISTAI ISITLVMAAV FIPVTFITGT TGVFYRQFGI TLTVSIILSA
INALTLSPAL CAIFLKPHNE EGKHKKGFMS RFYTAFNVAF ETMTVKYQKT TNFFVKKKWL
SAGMIVTFVA VLVYLMQTTP TGFVPAEDTG RVFVDISMPP ATSSEKTIEV ARQVDQILAN
VPEIDGRSMV AGYSFIGGQG SSYAMIIAAL KPFDERTGKG EDQNSIVGKL YGMTAGIKDA
RVIIFSPPMV PGFSVTGGFE LKLEDKTGGD IKNFEQVAGA FLGALNQRPE IQYAQTSFNT
AFPQYMVDVN TARCMQSGID VSTVLSTLQG YIGGYYASDF NRFGKQYRVM LQSEASFRGN
PDDLNSIKVR TSSGEMAPIT EFISLSRVYG PENITRFNMY TSINVTGNPN DGYSTGDAIN
AIKEVAAQTL PTGYAYEFSG ITREEINAGN QTIVIFALSL IFVFFFLAAQ YESYILPLSI
IFPLPIGIAG AFIFARLLGV ENNIYLQISL IMLIGLLAKN AILIVEFALQ RRQAGMSIVQ
AAIEGATARL RPILMTSFAF IVGLLPLVVG GGVGANGNRS IGTGAVGGML IGTLIGILVI
PAMFVVFQTL QEKIKKQETT EISDMNSLD
//
