ID   A0A420DT21_9RHOB        Unreviewed;       815 AA.
AC   A0A420DT21;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Dimethylglycine dehydrogenase {ECO:0000313|EMBL:RKE97310.1};
GN   ORFNames=C8N30_1905 {ECO:0000313|EMBL:RKE97310.1};
OS   Sulfitobacter guttiformis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Sulfitobacter.
OX   NCBI_TaxID=74349 {ECO:0000313|EMBL:RKE97310.1, ECO:0000313|Proteomes:UP000284407};
RN   [1] {ECO:0000313|EMBL:RKE97310.1, ECO:0000313|Proteomes:UP000284407}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11458 {ECO:0000313|EMBL:RKE97310.1,
RC   ECO:0000313|Proteomes:UP000284407};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RKE97310.1}.
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DR   EMBL; RAQK01000001; RKE97310.1; -; Genomic_DNA.
DR   RefSeq; WP_025064236.1; NZ_RAQK01000001.1.
DR   AlphaFoldDB; A0A420DT21; -.
DR   STRING; 1443111.Z949_3934; -.
DR   OrthoDB; 7156675at2; -.
DR   Proteomes; UP000284407; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000284407}.
FT   DOMAIN          9..377
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          380..434
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          436..701
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          727..807
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   815 AA;  90351 MW;  ABC144205058ED2B CRC64;
     MSDFPNTARV VIIGGGVVGT STLYHLARAG WKDCVLLEKN ELTAGSTWHA AGNCPNFSSS
     WAVMNMQRYG LEMYRTLGKD VDYPMNYHVT GSLRLAHSKE RMMEFERVAS MGAYQGLEMG
     MLTPAELKEY NPFMEVHDLE GGMWDPLDGD IDPAQLTQAL AKGAREAGGR IERFCPVVGL
     DRQDDEWIVK TEKGEIRAEI IVNCAGYYAQ RVGEMFKPFG GRTVPMVVMS HQYFLTEPIA
     ELETWTKEKG HKMPMIRDVD ISYYLRQDKH GLNLGPYERN CKAHWVTPDD PMPEDFSFQL
     YPDDLERLEF YIEDAMARVP ILGAAGVGRN INGPIPYAPD GLPMIGPMPG VKNAFEGHSF
     TFGIAQGGGA GKVLSEWIMH GETELDMWAV DPRRYTDYTD HDHCLAKALE TYGHEYAMHF
     PRHAWPAGRN RKLSPVHARI VEQGGQMGAY NGWERANWFA KDGDDTTEAA TQTWDRAGPW
     ARRIKEEVEA VRDGVGVLDL PGFSRFNLSG DGAAEYLRGR VSGGLPKIGR MNLGYFPDNR
     GRILTEMSIM RHGEDSFTLI TAATAQWHDF DVLKKDLPKG MSLSDHTTEY STLIVTGPKS
     RALFEALDAQ ADLLAAWLTV QPAVVAGVGC ALARVSFAGE LGWEIHAAIA DIPALYDAVI
     RAGAKPFGMF ALNSMRIEKG YRTWKGDLST DYTVLEAGLD RFVKLDKPQE FPGKAALAAE
     RAAGVKKRFV TMTVEAGDQD APYMSTVYYG GEVVGETTSG DWGYRVGKSI ALGTVRADLA
     VEGTQLDISI FGRMCKATIH ADRPLWDPEN ERIKA
//