ID A0A420J548_9PEZI Unreviewed; 846 AA.
AC A0A420J548;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Calcium permeable stress-gated cation channel 1 {ECO:0000313|EMBL:RKF81917.1};
GN ORFNames=GcM3_030014 {ECO:0000313|EMBL:RKF81917.1};
OS Golovinomyces cichoracearum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Golovinomyces.
OX NCBI_TaxID=62708 {ECO:0000313|EMBL:RKF81917.1, ECO:0000313|Proteomes:UP000283383};
RN [1] {ECO:0000313|EMBL:RKF81917.1, ECO:0000313|Proteomes:UP000283383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMSG3 {ECO:0000313|EMBL:RKF81917.1};
RX PubMed=30253736; DOI=10.1186/s12864-018-5069-z;
RA Wu Y., Ma X., Pan Z., Kale S.D., Song Y., King H., Zhang Q., Presley C.,
RA Deng X., Wei C.I., Xiao S.;
RT "Comparative genome analyses reveal sequence features reflecting distinct
RT modes of host-adaptation between dicot and monocot powdery mildew.";
RL BMC Genomics 19:705-705(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKF81917.1}.
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DR EMBL; MCBQ01003013; RKF81917.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A420J548; -.
DR STRING; 62708.A0A420J548; -.
DR Proteomes; UP000283383; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF83; CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000283383};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 529..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 627..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..668
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 689..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 715..736
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..202
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 224..422
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 434..708
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 846 AA; 96169 MW; EE11C7DCD048B06C CRC64;
MIMTRKFYIN ECEHYDPFDP HTGQEQIYVQ LTLSLALGLS ALFGFCFLRP RWKSLYAARK
RNCVHASALP ELPDTFFGWI PALHSVTEEQ ILGAAGLDAY VFLAFFKMSI KLFGTIFLIA
VLVLAPINNH FDWLPTFGNP TDNREISDLV SLQSTGIQNE TVSTLISAAG NNKNRSGPDP
TYLWVYLIFT YIFTGLAIFF MISQTKSIIE IRQKYLGRQS TVTDRTFKLS GVPPELRSET
KLKKLVESLC IGEVESVNLV RNWKKLDRLM DQRNSILRSL EELWTMYQKK LKLRSVPNNE
DRFVNRQYSI QDPQGERDTL LDQDHNDFAV DDLRPKTKVY HGIFWHRSRN VDAISYYEEK
LRSLDEKILT ARKKEYPSTP MAFITMDSTS ASQIAVQALL APLPTYLFAN LAPAPSDIVW
HNTYLPRHIR MMKAWAITAF IVILTIFWVV PVAAVAGLLD LCYIRSILPS LAEILSSHEI
LKSLTQTGLP TLVVSLLNIA VPFVYDLLSN YQGMISQGDV ELSLISKNFF FTFFNVFLTF
TVAGTATKFW STLQDSLKDT TFLAFKLAGS VQQLAVFYTN FILLQGIGLT PFRLLEFGSV
CLYPILLLRS KSPRDDWELN KPPVFKYGFF LPSAILVYIL CIVYSILPAG YMVLFFGVIY
FINSYYTYKY QLLYAMDHPQ HATGGAWPMI CYRILLGLGV FQIVMAGIIA LKNQIYAAGL
VVPLIPFTIW YSYYFARTYH PLMKFIALGS IRGKECIDLG NSGEGNEIYN SIDDRHGGFK
TIDEDREEGL LFVNPNFTMP LKQPWIEDSS GLSREPNGFD SGDFPVSNSI QENNFSSSLS
LGVTYD
//
