ID A0A420PN61_FUSOX Unreviewed; 2536 AA.
AC A0A420PN61;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Neurofibromin {ECO:0000313|EMBL:RKK94780.1};
GN ORFNames=BFJ68_g15033 {ECO:0000313|EMBL:RKK94780.1};
OS Fusarium oxysporum (Fusarium vascular wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=5507 {ECO:0000313|EMBL:RKK94780.1, ECO:0000313|Proteomes:UP000285860};
RN [1] {ECO:0000313|EMBL:RKK94780.1, ECO:0000313|Proteomes:UP000285860}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo_A28 {ECO:0000313|EMBL:RKK94780.1,
RC ECO:0000313|Proteomes:UP000285860};
RX PubMed=30202022; DOI=10.1038/s41598-018-30335-7;
RA Armitage A.D., Taylor A., Sobczyk M.K., Baxter L., Greenfield B.P.,
RA Bates H.J., Wilson F., Jackson A.C., Ott S., Harrison R.J., Clarkson J.P.;
RT "Characterisation of pathogen-specific regions and novel effector
RT candidates in Fusarium oxysporum f. sp. cepae.";
RL Sci. Rep. 8:13530-13530(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKK94780.1}.
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DR EMBL; MRCY01000143; RKK94780.1; -; Genomic_DNA.
DR VEuPathDB; FungiDB:FOC1_g10009526; -.
DR VEuPathDB; FungiDB:FOC4_g10004444; -.
DR VEuPathDB; FungiDB:FOIG_07895; -.
DR VEuPathDB; FungiDB:FOMG_08378; -.
DR VEuPathDB; FungiDB:FOXG_12635; -.
DR VEuPathDB; FungiDB:FOZG_01436; -.
DR VEuPathDB; FungiDB:HZS61_017557; -.
DR Proteomes; UP000285860; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR CDD; cd05392; RasGAP_Neurofibromin_like; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF150; INHIBITORY REGULATOR PROTEIN IRA1-RELATED; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00616; RasGAP; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
SQ SEQUENCE 2536 AA; 282847 MW; E168C91953FAE992 CRC64;
MNCDASLVGC LVDRLATRLP HRAGTSGQSL QQDDVLHVTR ATLVELGNTS ISTVIASLLV
LLEDLARPYA AVADHPSHIL ASELYIVAVI ADCCSSHWAS ISQDADVEPA PAPPPLDEVL
VSRLFDAFKH LLEPIPENCI LPAQTLLDQV STRNVSVARP ESSSVSSDAD SSPPSDERFA
ETLVEMDIHI KTVTEYVTTS SWTAAFDYLR NVIYTIRTSI VTQPGVSTPG STQDAERAAL
VVLRLLSFFW VDGPKLGQVI QEICSSFLHF RKPYQNTIAV VSPLLIMRWL DRFPREFVQL
HQLHKRLDGG ADTLFDMAQA ATDNGRRKGL FYPLQTTLLF LLPDVFEVAS NMREAKSSSM
VKKVTFLDGL RKASRNRNEQ AAYCLVSLLR AARHFDVESD SALVSYALDV QDEVRDAVFR
RLTASEYGLF DQDMMTAAFV SLTHLNLDTS VSGFVESCIA PNAPSSFKLA TVQGCTYFAQ
QPYALRYHEL FDAAIPFMRT QLETENAKAV STMGRQGSER TELVCSILQF LDASPARLLD
DLSKDGSNNS FFKSFLLCVL SENPAVRKLA TGVASRLFQG HLEAYRQFDT GHRFGTKELR
DDIWSRSSKV LLALCESVTS KKDDQSLRDL QDYLEARLLL LKNIPELAKV PEDAPDVINA
SSKLETTLLI SLCSASITTC QLVTSCTGLF IQECSIVDKH VESAKSSASV LRNAEVYREI
SSPAFRFTGL VAFQKRVRGL LRRMQFPTTG IVNAWETAFD RWLHLAKDVS TSTVEIVDGR
ALAEWRNYSG FLASLGGICT ADQAIILEEP ALGGLRWIDR VSSEHSEEPL LTRYLRLSIQ
LLACANVRVR EAMRDVLASE VSPALYYPLF RALESELEVL FTGALAPVEK DQDSEVVFAE
QAASLLRALV ERLESPSDLG AASSVHLGAL TLNFAKFLDG VTDTPNTLRV KIRVCHLCEV
VTKRKEHLNL RDDVRIRNQL LEYIFGWIAR PRSPQHGPGS RQDDTARVQK DLDKACLKSL
ADLTFRLPLQ PSESHTDAGM SEMKSQMFHT YFNRFLSLLN HEPSELTRTD TNLSVTLREE
SASNSDLAIT ILSNLLSANI DVGLKHSLNI GYHDNVEIRT AFVKVLYNIL IQGTEFSNLT
DSAVSEKYEE LLELLTSDLS LAISMAVACP STEVDELTIC LLTVFEQRGM IFELLEALIK
QEIEDTENEA EILRRGCVAT KMLSVYAKWK GASYIRTTLQ KVLERLMLTS KDLDLELDPA
RVSSTEELQK NALQLRIVAK VFIDDICASS SNIPPAFRKI CYTISNAVMP RFPDAKYTAV
GAFIFLRFFC PAIVAPEVEG LVSTAPSKEM RRGLLLIAKV IQNLANNVLF GAKEPYMFPL
NDFLTQNIYH VTTFLREISV PPNQLEVQGT TESFDFGSCV ALHRFLYDHW DHVRQTLISR
ERKDYGKTSG DVVRGRSPVL EPLRNLIANL GPPPLAVSWN RPQVSSNSPP LYSRFQNFML
RNAFRSTESF LTARAVYDGG ESKDGLSIIC VILRHIETES IDYDTLMYCY LKIASRLWHR
PFGILIDATC YNGRNEPQDD LFKKLELLTP SELSQNLSRI YVYNMNSAFK RCFRRLLRVC
TKNENGVFNP KNVEYHLIGS LQDLQAHFHL SQLHLPKETI SVVTDTRYVF QPITRLSKSK
GKIEVIIKVG SQFVQVTTTK KQEIFAGFRL GTTVNDIFRL GEVDEAPTSI QTEDDSAFGL
RADNGKIVMY FTSPKKSDVL QTIRGAKAKH GKDSRAHKSV ERLIRPQDVP GTLLNLSLAN
LSSHDHILRL SSYNLLGALC RAFKFSSASR IVCTKDVSVP LDPTRFVVDI SKELALSEPQ
LTSDFLTEFF VGWESFPDEQ KPLSLAYMAP WLPGLRTNIL TNELDGEKGR ERVAILFRKL
IDVTVQDHSL TFALEQSVWP RIVQDEILLE VFLDELLKSA MSYSAHDESL EVIASIVVGI
GTVTLRGKIL SRLRKALNRS SLRPTKYLPD NAVWSEICIL LRFCLALSFD NGVQSQLFLP
EIFHIVTMLA NTGTQEVRLL VYRLLVNTVH AVCTSFSLDD ARSSKLRASL DFLCDPRSDI
FTAPPTFPRD GASVSTSQDA GPALTATENL ASALFEICSV AAPTVDLANT WRSRWMSLVA
STAFQNNPAI QPRAFAVMGC LAREEVDDDL LYQVLVALRN SVNRFGEDHN SEMLVSIVTS
LSKMMAKLPS ASRYGLQLFW LAMSLVRLVP ATLFNSTAQF LEAVLANIST SEEFRGDSMA
SLLLQGRAPL DEAALPLEEI YGIHFEEETF HLAVCACLAR GLTDTMTRQI TMRVLSSFLE
MMTANVEGRE KAEMTQTSPY LSLLTARAVE NDEFKDSLWS AGINADELGF ANGMRKSPDL
EGMPDNVVLL ITAIELVDFQ YVEDSVQRRS LDWLNKLANE RPIVVEQLAG AIRSLLDDTL
LHSQNSATLR AAHTLLRALS STQQFSRAPG SMSTLTEVLD SMGFAGLWRS CSFGSMEDVN
RGYLELTERL IELIII
//
