ID   A0A420YB96_9PEZI        Unreviewed;       626 AA.
AC   A0A420YB96;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   22-FEB-2023, entry version 13.
DE   SubName: Full=Mg(2+) transporter {ECO:0000313|EMBL:RKU45146.1};
GN   Name=ALR1 {ECO:0000313|EMBL:RKU45146.1};
GN   ORFNames=DL546_005269 {ECO:0000313|EMBL:RKU45146.1};
OS   Coniochaeta pulveracea.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Coniochaetales; Coniochaetaceae; Coniochaeta.
OX   NCBI_TaxID=177199 {ECO:0000313|EMBL:RKU45146.1, ECO:0000313|Proteomes:UP000275385};
RN   [1] {ECO:0000313|EMBL:RKU45146.1, ECO:0000313|Proteomes:UP000275385}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CAB683 {ECO:0000313|EMBL:RKU45146.1,
RC   ECO:0000313|Proteomes:UP000275385};
RA   Borstlap C.J., De Witt R.N., Botha A., Volschenk H.;
RT   "Draft genome of the lignicolous fungus Coniochaeta pulveracea.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC       family. {ECO:0000256|ARBA:ARBA00009765}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RKU45146.1}.
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DR   EMBL; QVQW01000023; RKU45146.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A420YB96; -.
DR   STRING; 177199.A0A420YB96; -.
DR   Proteomes; UP000275385; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd12829; Alr1p-like; 1.
DR   Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR   Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR   InterPro; IPR044089; Alr1-like.
DR   InterPro; IPR045861; CorA_cytoplasmic_dom.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR   PANTHER; PTHR21535:SF55; MAGNESIUM TRANSPORTER ALR1-RELATED; 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR   SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275385};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        568..587
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        599..620
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          140..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          196..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..42
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..64
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..211
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   626 AA;  70347 MW;  591D625FF741AB3D CRC64;
     MSDHDETTPG SGFSTPVPEL DDHRRQASSV VRPDRPRRGT FDSLYGARRS SPAPSVTNPY
     GSATRVQDFE EAVVDDDVAD TSPTARRTRR PTVNSDYDHQ RGVSPPNSVK AFAEARRQER
     GLSFSGSTDQ DYEIRRTMSH ASHYSHRSRH HGGADDAASL STNKSAEEDV CFPIQNQRNG
     NNLVIDFDYL ESFMEAEKEE REDHQRHLST AKAYADARPT INHGGISSQS RMATSDGDLV
     DIPCSSSVHS EKMGDDDDDE SQPLKQVQTP VHDPSRVSFF SSAWESTIHA SDIEGLVLPG
     ENIRGLFSFP KGETDGVWWL NINKPSADEV RAVCRSFGIH PLTIEDITTQ EAREKIELFP
     LYYFACFKSF YLDKDPDTGE EEYMPFHVYV VVFREGVLSF SYANNSHASH VRQRITTLKD
     YLDLSSDWIC YALIDHIVDS FAPVISKIEH EADQIEDEVF VARTDDMHQF LRKIGSVRKN
     VMGLMRLLGG KADVLKGFTK RCNENYKVTP RMDIGLYLGD IQDHVVTMMT NLGHFEKMLS
     RSHSNYLAQI SIDGIAQSTE NNKVLSKITL LASIIVPLNV VTGLFGMNVK VPFRDAENLI
     PFFVILATLL VFCAVAAAYA RRLRWI
//