ID   A0A420YCT4_9PEZI        Unreviewed;       929 AA.
AC   A0A420YCT4;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=PRP1 splicing factor N-terminal domain-containing protein {ECO:0000259|Pfam:PF06424};
GN   ORFNames=DL546_006299 {ECO:0000313|EMBL:RKU45686.1};
OS   Coniochaeta pulveracea.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Coniochaetales; Coniochaetaceae; Coniochaeta.
OX   NCBI_TaxID=177199 {ECO:0000313|EMBL:RKU45686.1, ECO:0000313|Proteomes:UP000275385};
RN   [1] {ECO:0000313|EMBL:RKU45686.1, ECO:0000313|Proteomes:UP000275385}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CAB683 {ECO:0000313|EMBL:RKU45686.1,
RC   ECO:0000313|Proteomes:UP000275385};
RA   Borstlap C.J., De Witt R.N., Botha A., Volschenk H.;
RT   "Draft genome of the lignicolous fungus Coniochaeta pulveracea.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Associated with the spliceosome.
CC       {ECO:0000256|ARBA:ARBA00011524}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RKU45686.1}.
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DR   EMBL; QVQW01000019; RKU45686.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A420YCT4; -.
DR   STRING; 177199.A0A420YCT4; -.
DR   Proteomes; UP000275385; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 5.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR010491; PRP1_N.
DR   InterPro; IPR045075; Syf1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR11246; PRE-MRNA SPLICING FACTOR; 1.
DR   PANTHER; PTHR11246:SF1; PRE-MRNA-PROCESSING FACTOR 6; 1.
DR   Pfam; PF06424; PRP1_N; 1.
DR   Pfam; PF13428; TPR_14; 1.
DR   Pfam; PF13432; TPR_16; 1.
DR   Pfam; PF14559; TPR_19; 1.
DR   SMART; SM00386; HAT; 12.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF48452; TPR-like; 4.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   mRNA processing {ECO:0000256|ARBA:ARBA00023187};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275385};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          12..165
FT                   /note="PRP1 splicing factor N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06424"
FT   REPEAT          693..726
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          1..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          109..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        36..78
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   929 AA;  104088 MW;  08D262E5E43A7977 CRC64;
     MTGRRDFLSQ PAPENYVAGL GRGATGFTTR SDLGPAREGP TEEQIKAAVA KRSKELGFTD
     GKDKDDDDKE DDPRFQDPDN EVGLFAGGIY EKDDEEADEI WRNIDDRMAK RRQKQREARE
     NAEREEYERK NPKIQAQFAD LKRALGTVTD EEWANLPDAK DFTGRNKRAR AARHERFYAV
     PDSVLAAAGT AGEMGTTVAD EGTATEPNQG NGTTTDFAKI GAARDKVLQA RLDQASQVSS
     GTSTVLGSAS SIDAKGYLTS LAKREGAEQS IGDIEKFRKM FKSAVDSNPT NASAWIAAAR
     LEEYAGKQVA ARTLMADGCK HCPKSEDAWI ENIRLNENRN AKIIAAAAIK ANPRSVRLWV
     EAMRLESDNR SKKKVIRMAL EQIPESEALW KEAVNLEDDP EDARLLLAKA TELIPGSVDL
     WLALARLETP QNARKVLNKA GKAIPTSHEI WIAAARLEEQ LGEGTKTSVM KNAVRFLAKR
     NAMPKREEWI TEAEKCEEDG AVLTCGNIIR ETLGWGLDED DDRKDVWIED AKSSTVRGKF
     ETARAIYAYA LRVFPTSKTL WMAAVELERN HGTKEALCQV LEKAVEACPH SEVLWLMLAK
     ERWQGGDLDE ARKVLGRAFN QNPDNEDIWL AAVKLESDND FTDQARELLK TARQNAPTDR
     VWMRSVAFER QLGDNEAALD LVQDAILLFP SAAKLWMMKG QIYEDLEKVP QAREAYSTGV
     KAVPSSVPLW LLFSRLEERN GMVVKARSVL DRARQAVPKS PELWCELIRV ERRAGNLNQA
     KSLMATALQQ MPKSGLLWSE RILHLEPRTQ RRTLIVEALK QVESDPTVLT TAARIFWAER
     KLEKAQNWFE RALVLDSDVG DTWAWYYKFL LQHGTEGKRD ELVSKLKLVE PRHGESWQPV
     AKDPKNAKKK PEEILRLVAA SLPNQPVGV
//