ID A0A421ETC0_9STRA Unreviewed; 434 AA.
AC A0A421ETC0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Tubulin gamma chain {ECO:0000256|RuleBase:RU000352};
GN ORFNames=BBI17_005265 {ECO:0000313|EMBL:RLM96940.1}, BBO99_00004811
GN {ECO:0000313|EMBL:RLN80027.1}, JM16_002644
GN {ECO:0000313|EMBL:KAG2524157.1}, JM18_004660
GN {ECO:0000313|EMBL:KAG2522509.1};
OS Phytophthora kernoviae.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=325452 {ECO:0000313|EMBL:RLM96940.1, ECO:0000313|Proteomes:UP000285883};
RN [1] {ECO:0000313|EMBL:KAG2522509.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2524157.1}, and NZFS 3630
RC {ECO:0000313|EMBL:KAG2522509.1};
RX PubMed=26981359;
RA Studholme D.J., McDougal R.L., Sambles C., Hansen E., Hardy G., Grant M.,
RA Ganley R.J., Williams N.M.;
RT "Genome sequences of six Phytophthora species associated with forests in
RT New Zealand.";
RL Genom Data 7:54-56(2015).
RN [2] {ECO:0000313|Proteomes:UP000285624, ECO:0000313|Proteomes:UP000285883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Chile2 {ECO:0000313|EMBL:RLM96940.1}, and Chile4
RC {ECO:0000313|EMBL:RLN80027.1};
RA Studholme D.J., Sanfuentes E., Panda P., Hill R., Sambles C., Grant M.,
RA Williams N.M., Mcdougal R.L.;
RT "Genome sequencing of oomycete isolates from Chile give support for New
RT Zealand origin for Phytophthora kernoviae and make available the first
RT Nothophytophthora sp. genome.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KAG2522509.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NZFS 2646 {ECO:0000313|EMBL:KAG2524157.1}, and NZFS 3630
RC {ECO:0000313|EMBL:KAG2522509.1};
RA Studholme D.J.;
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Tubulin is the major constituent of microtubules. The gamma
CC chain is found at microtubule organizing centers (MTOC) such as the
CC spindle poles or the centrosome, suggesting that it is involved in the
CC minus-end nucleation of microtubule assembly.
CC {ECO:0000256|ARBA:ARBA00004079}.
CC -!- SIMILARITY: Belongs to the tubulin family.
CC {ECO:0000256|ARBA:ARBA00009636, ECO:0000256|RuleBase:RU000352}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLM96940.1}.
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DR EMBL; JPWU03000210; KAG2522509.1; -; Genomic_DNA.
DR EMBL; JPWV03000121; KAG2524157.1; -; Genomic_DNA.
DR EMBL; MAYM02002293; RLM96940.1; -; Genomic_DNA.
DR EMBL; MBDN02000123; RLN80027.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A421ETC0; -.
DR STRING; 325452.A0A421ETC0; -.
DR Proteomes; UP000285624; Unassembled WGS sequence.
DR Proteomes; UP000285883; Unassembled WGS sequence.
DR Proteomes; UP000785171; Unassembled WGS sequence.
DR Proteomes; UP000792063; Unassembled WGS sequence.
DR GO; GO:0000930; C:gamma-tubulin complex; IEA:InterPro.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR CDD; cd02188; gamma_tubulin; 1.
DR Gene3D; 1.10.287.600; Helix hairpin bin; 1.
DR Gene3D; 3.30.1330.20; Tubulin/FtsZ, C-terminal domain; 1.
DR Gene3D; 3.40.50.1440; Tubulin/FtsZ, GTPase domain; 2.
DR InterPro; IPR002454; Gamma_tubulin.
DR InterPro; IPR008280; Tub_FtsZ_C.
DR InterPro; IPR000217; Tubulin.
DR InterPro; IPR037103; Tubulin/FtsZ-like_C.
DR InterPro; IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
DR InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR InterPro; IPR023123; Tubulin_C.
DR InterPro; IPR017975; Tubulin_CS.
DR InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR PANTHER; PTHR11588; TUBULIN; 1.
DR PANTHER; PTHR11588:SF7; TUBULIN GAMMA CHAIN; 1.
DR Pfam; PF00091; Tubulin; 2.
DR Pfam; PF03953; Tubulin_C; 1.
DR PRINTS; PR01164; GAMMATUBULIN.
DR PRINTS; PR01161; TUBULIN.
DR SMART; SM00864; Tubulin; 1.
DR SMART; SM00865; Tubulin_C; 1.
DR SUPFAM; SSF55307; Tubulin C-terminal domain-like; 1.
DR SUPFAM; SSF52490; Tubulin nucleotide-binding domain-like; 1.
DR PROSITE; PS00227; TUBULIN; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU000352};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU000352};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000352};
KW Reference proteome {ECO:0000313|Proteomes:UP000285624}.
FT DOMAIN 48..219
FT /note="Tubulin/FtsZ GTPase"
FT /evidence="ECO:0000259|SMART:SM00864"
FT DOMAIN 221..362
FT /note="Tubulin/FtsZ 2-layer sandwich"
FT /evidence="ECO:0000259|SMART:SM00865"
SQ SEQUENCE 434 AA; 48536 MW; AF13E14C435C75D9 CRC64;
MPREIITLQA GQCGNQIGME FWKQLCAEHG ISADGIVQDF ANSGHDRKDV FFYQADDEHY
IPRALLMDLE PRVINSISTS TFRNLYNPEN FFVSKEGGGA DSLEGFVLCH SIAGGTGSGM
GSYLLENLND HFPKKLIQTY SVFPNQSDFQ SDVVVQPYNS LLTMKRLVLN ADSVVVLDNT
ALNRIAVERL RVENPTVSQL NSLVSTVMAA STTTLRYPGY MNNDLIGLVA SLIPTPRCHF
LMTGYTPLTI DTQVSAVRKT TVLDVMRRLL QPKNIMVSTS TKTGCYISIL NIIQGDVDPT
QVHKSLQRIR ERKLARFIPW GPASIQVALS RKSPYVETAH KVNGLMLANH TSIGALFHKL
LLQYDRLKKH GAFIENYRKE PMFAENLDEF DSAREVVQNL VDEYKASERA DYATWGQPPQ
AIANSAMDDV RMAH
//
