ID   A0A421J8E1_9ASCO        Unreviewed;       634 AA.
AC   A0A421J8E1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=DNA polymerase epsilon subunit B {ECO:0000256|ARBA:ARBA00016011};
DE   AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|ARBA:ARBA00032930};
GN   ORFNames=JA9_000097 {ECO:0000313|EMBL:RLV84884.1};
OS   Meyerozyma sp. JA9.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=2028340 {ECO:0000313|EMBL:RLV84884.1, ECO:0000313|Proteomes:UP000286412};
RN   [1] {ECO:0000313|EMBL:RLV84884.1, ECO:0000313|Proteomes:UP000286412}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JA9 {ECO:0000313|EMBL:RLV84884.1,
RC   ECO:0000313|Proteomes:UP000286412};
RA   Formighieri E.F., Steindorff A.S., Trichez D., Almeida J.R.;
RT   "Physiological and comparative genomic analysis of newly identified yeasts
RT   Spathaspora sp. JA1 and Meyerozyma sp. JA9 reveals insights into xylitol
RT   production.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC       {ECO:0000256|ARBA:ARBA00009560}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RLV84884.1}.
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DR   EMBL; NSDU01000017; RLV84884.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A421J8E1; -.
DR   STRING; 2028340.A0A421J8E1; -.
DR   Proteomes; UP000286412; Unassembled WGS sequence.
DR   GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR016266; POLE2.
DR   PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR   PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286412}.
FT   DOMAIN          334..593
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
SQ   SEQUENCE   634 AA;  71496 MW;  92C45634C37AB820 CRC64;
     MDRTALPVKL QPSTLRPFAY RILSKKHGLN VQTDALKILT ETISARFGYD WKNQNSQSLL
     EDIAKLWKSQ DRGLFIDGQG LNQVLKDISG KNEPVLAERS DTLADVGAAN DQEIDWKDFF
     KVITPPQQPN YRFDRQRKQF SLEKPTSLSD AVTTNISYFN NRYHLLADRL SRNENFQKSS
     LASFSTTTVQ STEITLIKNV LGRDGSKFIL FGLLSKNANG DYILEDATDH IELNLSQAHK
     TEGSYYCSGM FVVVEGIYSA SGGTLSSANL IGGCFHVSHI GQPPAERRDL SLENFGNLDF
     VGINSDTSTR LNKTLKKRLI SMEKSHVDHK IVFLGANCFL DDSRVLEGLK KLFSTFERDI
     VDGEKAPLAI VMYGSFISGP MTATSTSIST ISNSESYKNN FDEFTSILSK FKYLIQDTKF
     VMIPGPNDPW QATYSLGSSN LNALPQQPIP SLFASRLERL LPKGNLILAF NPSRLCYLSQ
     EIVMLRDDIT PKLKRNDIVF NHDLELEKLR LNRDIEREAS GGTITLDTID TSEQHVSTKV
     KQARKLVKTL LDQGTLQPFL RDLRLIDTTY DYALRIEPLP SAIVLNDSTF ENFDVTYNGT
     RVVNVGPLTS STKRINYMEY YPSKKRFVVK EVHY
//