ID A0A421JC18_9ASCO Unreviewed; 462 AA.
AC A0A421JC18;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Arginosuccinase {ECO:0000256|ARBA:ARBA00032749};
GN ORFNames=JA9_004634 {ECO:0000313|EMBL:RLV86379.1};
OS Meyerozyma sp. JA9.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=2028340 {ECO:0000313|EMBL:RLV86379.1, ECO:0000313|Proteomes:UP000286412};
RN [1] {ECO:0000313|EMBL:RLV86379.1, ECO:0000313|Proteomes:UP000286412}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JA9 {ECO:0000313|EMBL:RLV86379.1,
RC ECO:0000313|Proteomes:UP000286412};
RA Formighieri E.F., Steindorff A.S., Trichez D., Almeida J.R.;
RT "Physiological and comparative genomic analysis of newly identified yeasts
RT Spathaspora sp. JA1 and Meyerozyma sp. JA9 reveals insights into xylitol
RT production.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the lyase 1 family. Argininosuccinate lyase
CC subfamily. {ECO:0000256|ARBA:ARBA00010755}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLV86379.1}.
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DR EMBL; NSDU01000010; RLV86379.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A421JC18; -.
DR STRING; 2028340.A0A421JC18; -.
DR UniPathway; UPA00068; -.
DR Proteomes; UP000286412; Unassembled WGS sequence.
DR GO; GO:0004056; F:argininosuccinate lyase activity; IEA:InterPro.
DR GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR CDD; cd01359; Argininosuccinate_lyase; 1.
DR Gene3D; 1.10.40.30; Fumarase/aspartase (C-terminal domain); 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR HAMAP; MF_00006; Arg_succ_lyase; 1.
DR InterPro; IPR029419; Arg_succ_lyase_C.
DR InterPro; IPR009049; Argininosuccinate_lyase.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR020557; Fumarate_lyase_CS.
DR InterPro; IPR000362; Fumarate_lyase_fam.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR NCBIfam; TIGR00838; argH; 1.
DR PANTHER; PTHR43814; ARGININOSUCCINATE LYASE; 1.
DR PANTHER; PTHR43814:SF1; ARGININOSUCCINATE LYASE; 1.
DR Pfam; PF14698; ASL_C2; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR PRINTS; PR00145; ARGSUCLYASE.
DR PRINTS; PR00149; FUMRATELYASE.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
DR PROSITE; PS00163; FUMARATE_LYASES; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:RLV86379.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000286412}.
FT DOMAIN 11..306
FT /note="Fumarate lyase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00206"
FT DOMAIN 369..437
FT /note="Argininosuccinate lyase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14698"
SQ SEQUENCE 462 AA; 51330 MW; 8AD49EE3A4FBA6B2 CRC64;
MSDTPAKLWG GRFTGATDPL MDLYNASLPY DKKMYAADLH GTAIYTQGLH KLGILSTDEL
ASIQQGLKVV EKEWESGTFE EKPGDEDIHT ANERRLGEVI GKHIAGKVHT GRSRNDQVAT
DMRIFVRETL TTLLQYLSQL IGTIVNRAGQ EIDVLMPGYT HLQRAQPIRW AHWLSSYATY
FTEDYKRLKE LLVRVNQSPL GSGALAGHPY GIDREFLAEN LGFDGVIGNS LVAVSDRDFV
VESLFWCSLF MNHISRFSED LIIYSTAEFG FVKLADAYST GSSLMPQKKN PDSLELLRGK
CGRVFGSLAG FMMSIKSIPS TYNKDMQEDK EPLFDALTTV EHSILIATGV ISSLSINKEK
MEAALTMDML ATDLADYLVM KGVPFRETHH ISGECVSQAE KLNLSGIDQL SMEQLQAIDS
RFGDDVKDVF NFEASVERRN ATGGTAKSAV LKQLESLKKQ IN
//
