ID A0A421JM54_9ASCO Unreviewed; 763 AA.
AC A0A421JM54;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=MutS protein 4 {ECO:0000313|EMBL:RLV91869.1};
GN ORFNames=JA1_003559 {ECO:0000313|EMBL:RLV91869.1};
OS Spathaspora sp. JA1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Spathaspora.
OX NCBI_TaxID=2028339 {ECO:0000313|EMBL:RLV91869.1, ECO:0000313|Proteomes:UP000285775};
RN [1] {ECO:0000313|EMBL:RLV91869.1, ECO:0000313|Proteomes:UP000285775}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JA1 {ECO:0000313|EMBL:RLV91869.1,
RC ECO:0000313|Proteomes:UP000285775};
RA Formighieri E.F., Steindorff A.S., Trichez D., Almeida J.R.;
RT "Physiological and comparative genomic analysis of newly identified yeasts
RT Spathaspora sp. JA1 and Meyerozyma sp. JA9 reveals insights into xylitol
RT production.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLV91869.1}.
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DR EMBL; NSGQ01000030; RLV91869.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A421JM54; -.
DR STRING; 2028339.A0A421JM54; -.
DR Proteomes; UP000285775; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000285775}.
FT DOMAIN 606..622
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 763 AA; 86789 MW; ED223921FB025CBB CRC64;
MSSRINSSYG FVSETSSSSV KRRRVPPSDE NNEIVMSIYK SKSDSMDMGL AILNCKTFEL
TLLNFCDSST FIRTINQIKV YVPTVILLPE VQMNPQMDKL KYIVNSNVND KIKVKLQKLK
CFNSETGLNN TKIFCECDEL ALQETLNGKE LSLAAFNSCI EYCLSLKLFR PRTKMRLKFG
NCESTMLIDT CTIRDLELVD SVCDHGISLF TFLDRYTESI KLRLESVQEL ISNEDILASL
RSHLKTLHDL EKMFSSFLDK SDIPGNQDQR INNLIMLKST LDQTTQICKY LEDSKSHLLV
QIKQIISHEY IQAALTAISH YIQDDCQWAK NNLELTNQKV NAIKTGVNGF LDVSRQLYEA
LLEEVNDLVS NLADNFELSI DFRYEPVRGF FMRIKDYSGH LNDLPPVFIN KVKKRKLIEC
TTINLMKQSS RFNDVVLEIN ILNNNIIEEL HTTISSYIPI FLMICEAIGT LDLLCGFASF
VAQQKRPYVC PEFGKDLNIR RSRHPILEAS IPGFVPNDYS CIREISRFQI ITGANMSGKS
VYLRQIAYLA IMAQIGCFIP ADYAVMSVFE GLYTRISADN TEVNASSFSR EMTEIATIMK
MATNKSLVII DELGRGSSYT DGFSICLAVL ESFISGEAVV FSSTHFREIA AILGNKSCVV
ASHMETTDIN GKLEMKYNLL KGKVETEGYG IRYAEYSKLL PDMLMENAKD LATQIKKLRT
VEGNEQAKML SRRRKLILEF YFALNHIREL EGDANFKINS WKK
//
