ID A0A421JTZ1_9ASCO Unreviewed; 742 AA.
AC A0A421JTZ1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 28-JUN-2023, entry version 15.
DE SubName: Full=Nucleoporin NUP2 {ECO:0000313|EMBL:RLV95275.1};
GN ORFNames=JA1_001263 {ECO:0000313|EMBL:RLV95275.1};
OS Spathaspora sp. JA1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Spathaspora.
OX NCBI_TaxID=2028339 {ECO:0000313|EMBL:RLV95275.1, ECO:0000313|Proteomes:UP000285775};
RN [1] {ECO:0000313|EMBL:RLV95275.1, ECO:0000313|Proteomes:UP000285775}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JA1 {ECO:0000313|EMBL:RLV95275.1,
RC ECO:0000313|Proteomes:UP000285775};
RA Formighieri E.F., Steindorff A.S., Trichez D., Almeida J.R.;
RT "Physiological and comparative genomic analysis of newly identified yeasts
RT Spathaspora sp. JA1 and Meyerozyma sp. JA9 reveals insights into xylitol
RT production.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|ARBA:ARBA00004567}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RLV95275.1}.
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DR EMBL; NSGQ01000006; RLV95275.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A421JTZ1; -.
DR STRING; 2028339.A0A421JTZ1; -.
DR Proteomes; UP000285775; Unassembled WGS sequence.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd13181; RanBD_NUP2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR015007; NUP2/50/61.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000156; Ran_bind_dom.
DR PANTHER; PTHR38697; NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG); 1.
DR PANTHER; PTHR38697:SF1; NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG); 1.
DR Pfam; PF08911; NUP50; 1.
DR Pfam; PF00638; Ran_BP1; 1.
DR SMART; SM00160; RanBD; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50196; RANBD1; 1.
PE 4: Predicted;
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|ARBA:ARBA00023132};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00023132};
KW Reference proteome {ECO:0000313|Proteomes:UP000285775};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022816}.
FT DOMAIN 610..742
FT /note="RanBD1"
FT /evidence="ECO:0000259|PROSITE:PS50196"
FT REGION 153..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 211..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..254
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..402
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..423
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..447
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..537
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 742 AA; 80315 MW; ADAEB32010BE393D CRC64;
MDRKRNAIDQ INRDDFERGY DDVEDVPAAT MKASDEVLAK RKIIMPKRRI DGSNSTGISF
GGAPQASNPF GFMKSAGGID QKNAKIRALN EQFVNAVNKK NVPNSLVDYT SVAESYIKYY
KSIHEDSTAK PVEEPKSTFK MATHTPVVGA TTTAPTLFSS KPTPPTATTT TTTTTTGGPQ
FSAPTTTSFQ FQAKPQSQAA FSFSAGISQP PTSAPAFGIP SKAPDVQPVQ TKEEPIMITS
ESEDDDEDMD EDEDKPEIKV QGPQFTLTSK PTTKSGPFTF DPKKLAKINA PDSDDSEDEV
VIKGPTFQFN KPIVDSVFKL GEGTTKDKPA FSFGSNVEKK DEKPVVSFGA TTEKPAFSFG
SGSQPSENKP AFSFNSAVPE KKEDKPAFSF SQITEKKEDK PGFSFGSSNS TNDKPALFSF
TQPSSEEKED KPSFSFTPSE KKDDKPGFSF GSAQNNNSDK PSFSFTSSTN KETNPFSFGS
SAPPPASSDK SNEKPGFSFG SSSTVGAETR PFSFGSSSET ATKPLFSSTT DKQEEKPAFS
FGTQPAVSEP PKFNFGGASS AFNNKSETET AKPVFNFAFN PSKSSNAGLF VPAESEEDDD
KVPEEETGGD FAPIAQLSSE KMENVGTGEE DEELIYSKRC KLMQLDPKDK KNPYVNKGVG
DLKILKHKET QKTRILIRTD GEVGRVLLNT LISKDLKYET MGNGSLVRIP TVDNSKQIVT
YVVRVKTPTD GSELSTAITN VQ
//
