ID A0A422NK00_TRYRA Unreviewed; 729 AA.
AC A0A422NK00;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Rib72 protein-like protein {ECO:0000313|EMBL:RNF05786.1};
GN ORFNames=TraAM80_04319 {ECO:0000313|EMBL:RNF05786.1};
OS Trypanosoma rangeli.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=5698 {ECO:0000313|EMBL:RNF05786.1, ECO:0000313|Proteomes:UP000283634};
RN [1] {ECO:0000313|EMBL:RNF05786.1, ECO:0000313|Proteomes:UP000283634}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM80 {ECO:0000313|EMBL:RNF05786.1,
RC ECO:0000313|Proteomes:UP000283634};
RX PubMed=30355302; DOI=10.1186/s12864-018-5112-0;
RA Bradwell K.R., Koparde V.N., Matveyev A.V., Serrano M.G., Alves J.M.,
RA Parikh H., Huang B., Lee V., Espinosa-Alvarez O., Ortiz P.A.,
RA Costa-Martins A.G., Teixeira M.M., Buck G.A.;
RT "Genomic comparison of Trypanosoma conorhini and Trypanosoma rangeli to
RT Trypanosoma cruzi strains of high and low virulence.";
RL BMC Genomics 19:770-770(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNF05786.1}.
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DR EMBL; MKGL01000125; RNF05786.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A422NK00; -.
DR VEuPathDB; TriTrypDB:TRSC58_03863; -.
DR OMA; HTRAYME; -.
DR OrthoDB; 143973at2759; -.
DR Proteomes; UP000283634; Unassembled WGS sequence.
DR GO; GO:0005930; C:axoneme; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 2.30.29.170; -; 3.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR006602; DM10_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR040193; EFHC1/EFHC2/EFHB.
DR PANTHER; PTHR12086; EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12086:SF16; RIB72 PROTEIN-LIKE PROTEIN; 1.
DR Pfam; PF06565; DM10_dom; 3.
DR SMART; SM00676; DM10; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS51336; DM10; 3.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000283634}.
FT DOMAIN 83..183
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 249..359
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 419..514
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 572..607
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 729 AA; 83314 MW; 747B1D7724CCFF59 CRC64;
MHVPMEKTVY NALPMLPGFS FPELHPPATH FRRHYCSIHG GTRSVLDAHT TRRRGDDDGQ
SGECGGLSRA EIFAKFPEWK SLDDKVLRFF AYYVERVDES MVERMRVRKV KIHFYLRDGT
LVVVETPAVG NSGLPAGTIV SRCKIDGVDF FALYVGSSIR VRGLEYMIVD CDAFTRDFCA
AMGMTQPEPL GYPEDAFEKS VKVEKAPMDE HHIAMRRTME TIAAGVTGVK ATLLSPEERN
KARNFFEHDR EVLRFLAVWD KRLFRLQYYI ADKTISVMLE HARNDGRDPN PVFIRRTPIP
KDPKVALRDI ETLNAPLGPP VAYVTDEDLR TGQTVNLFTR DFYIFDCDPY TRDYYEARGI
KQPAFPKPST EADALVPKTE APPPTTTQLP SIKSVQGAST MVFEDTVAHK DRLKLTRFMN
DVFRFSARRV NPSPEDEGRR FLFCYYLADD TVSLFELVVA NSGHVGGKCF ARSVVPEINE
PGKLYVGAKV KLAGATYELI EMDERTKRYI AMGMPIMEES YFQTQDLIER VRHVILQRFL
GATDVFRRFK STTEGLNRED LKRLFAECGT RVDAAELDRV MERLDQDKDG IVSLSELVEN
LLLQQFVSDF VAKNERRDGI EEGPLRPFRS LEANKTAARE ADEALRRLIS RSEARRLLLI
RAFRTTSNNT YDGHLGVEDF RRALRERLNL SLTDDEVDAL TYKFFYTPGS GNWTARRLPV
KEIQRIIMC
//
