ID   A0A423PFH1_9GAMM        Unreviewed;      1037 AA.
AC   A0A423PFH1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Metal transporter {ECO:0000313|EMBL:ROO24330.1};
GN   ORFNames=SAJA_13975 {ECO:0000313|EMBL:ROO24330.1};
OS   Salinisphaera japonica YTM-1.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Salinisphaerales;
OC   Salinisphaeraceae; Salinisphaera.
OX   NCBI_TaxID=1209778 {ECO:0000313|EMBL:ROO24330.1, ECO:0000313|Proteomes:UP000285310};
RN   [1] {ECO:0000313|EMBL:ROO24330.1, ECO:0000313|Proteomes:UP000285310}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YTM-1 {ECO:0000313|EMBL:ROO24330.1,
RC   ECO:0000313|Proteomes:UP000285310};
RA   Lai Q., Li C., Shao Z.;
RT   "Salinisphaera japonica YTM-1 Genome Sequencing.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROO24330.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AYKG01000067; ROO24330.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A423PFH1; -.
DR   InParanoid; A0A423PFH1; -.
DR   OrthoDB; 9758757at2; -.
DR   Proteomes; UP000285310; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR004763; CusA-like.
DR   NCBIfam; TIGR00914; 2A0601; 1.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000285310};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        345..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        368..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        394..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        443..463
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        475..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        531..553
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        870..889
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        896..916
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        922..947
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        968..987
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        999..1022
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1037 AA;  112472 MW;  1CD7B8058CAFE52A CRC64;
     MISRFVRMAL ANRVLTLVAV TALALAGVYS FSNVPIDSYP DVTPSMVQIY TSSPGLSPVD
     VETQVSYPVS IAMYGLPGLE RVQSTSIFGL SRVNVYFEDG TDIYFARRLV MERLAKAREQ
     IPEGLGEPQL GPITSGLGRV MMYTVENTQP GQYTPTELRT AQDWIVKPQL RTVSGVTGVL
     SIGGYEKQYQ ITLDPNALSA RNITVAEVRR AIAENNRNVG GSFINRGGEE YIIRGYGWVS
     PGEEGLDDLR TIQVTENNGT PVYIADIAEV GFGPAIRRGT MIADGEEAVG GFVLKLFGSN
     TQALLDKVEA KVDTINQALP EGMRVKPFYS QASLIEKASG TVEDALLEGS ILVFVLLYLF
     LGNLRSTLIV IASLPLSVLI AFIAMDYVGL SANLMSLGGL AIGIGMMVDG SVVMIENIFR
     HMEERADEDV SHLRLVGEAA AEIAQPVTFA IAIIVLVFTP LFTLQGTEGK LFSPMAYTIC
     FALVGALVMA LTFVPVMASF LFKKGSAHGE PRLIGWLKAG YRPVRDAAIK APIAVLSLAI
     VLFLSSLVIF PSLGTEFIPT LREGTFMVRS TLPPGASLKT TQAYAKRVQA VMREFPEVEG
     VYSRVGRAEV GGDPEPVNVI ASVVNLKPLD KWRAGRDYEQ LQNAMAQRVG DAIPGLANNF
     SQPIQLRTDE LLSGVLAQVV VSIYGDDLDK LAKTGEEIAA IARDVPGAAD VRVQQQGGKP
     QIVVRPDREA LARYGIPLDE VLGVVETGIG GAAVGQVFEN IRRFDIFLRF DEAARNRIDA
     IRNLTFRTSE GAMIPLSRVA DVEVYRGPKK ISRAKASRRL FVQLNVRGRD MGGVVRDIQQ
     RVADNVALPP GYFVEYGGQF ENQRRAMARL YVVVPITMAL IFLLLFVAFS SLRYAALIYL
     NVPFAITGGI FALWMSGLYL SVAGAVGFIA VFGVAVLNGV VLVSYINQLR EQGMSTEDAV
     RIGAEHRLRP VLMTASVAIL GLVPLLLANG IGANVQRPLA AVVVGGLITS TLLTLLVLPA
     IYRWFAEPRR AEDVERR
//