ID A0A423PMZ0_9GAMM Unreviewed; 370 AA.
AC A0A423PMZ0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=SAJA_10440 {ECO:0000313|EMBL:ROO26881.1};
OS Salinisphaera japonica YTM-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Salinisphaerales;
OC Salinisphaeraceae; Salinisphaera.
OX NCBI_TaxID=1209778 {ECO:0000313|EMBL:ROO26881.1, ECO:0000313|Proteomes:UP000285310};
RN [1] {ECO:0000313|EMBL:ROO26881.1, ECO:0000313|Proteomes:UP000285310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YTM-1 {ECO:0000313|EMBL:ROO26881.1,
RC ECO:0000313|Proteomes:UP000285310};
RA Lai Q., Li C., Shao Z.;
RT "Salinisphaera japonica YTM-1 Genome Sequencing.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROO26881.1}.
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DR EMBL; AYKG01000032; ROO26881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A423PMZ0; -.
DR InParanoid; A0A423PMZ0; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000285310; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000285310}.
FT DOMAIN 18..354
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 370 AA; 40102 MW; FDB3E90A880CF1AB CRC64;
MSRIHENEVQ LNDDRILGRL TLDNPKALNA VRLDMIEPML SAIHAWEARP EVVAILIDAE
GDKAFCAGGD IVNLYRSIIG EIEADYPQRF FTEEYRLCHD LHRLATPVVA WGHGIVMGGG
CGLFAGASHR VVTETTRLAM PEIKIGLFPD CGATWFFSRL PHYLARFISL TGATLDSADV
LFAGLAEHGI AHREKQAVIT ALETAQDWDQ PHRTVDRILA AAEQRSPAAD TADSRLMAAA
PTIREAARGS DLGDIVAGLT ALAETGDDWL AESAGSLAAG CPTTAHLIHD QLETGRYLSL
AQAVQRELAM ALACCRHADF AEGVRALLVD KDKTPVWQYD SVAAVPGQHV ADHFVPDWSG
AHPLADLGQR
//
