ID A0A423PQT3_9GAMM Unreviewed; 402 AA.
AC A0A423PQT3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:ROO27975.1};
GN ORFNames=SAOR_06600 {ECO:0000313|EMBL:ROO27975.1};
OS Salinisphaera orenii MK-B5.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Salinisphaerales;
OC Salinisphaeraceae; Salinisphaera.
OX NCBI_TaxID=856730 {ECO:0000313|EMBL:ROO27975.1, ECO:0000313|Proteomes:UP000283993};
RN [1] {ECO:0000313|EMBL:ROO27975.1, ECO:0000313|Proteomes:UP000283993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MK-B5 {ECO:0000313|EMBL:ROO27975.1,
RC ECO:0000313|Proteomes:UP000283993};
RA Lai Q., Li C., Shao Z.;
RT "Salinisphaera orenii MK-B5 Genome Sequencing.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROO27975.1}.
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DR EMBL; AYKH01000011; ROO27975.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A423PQT3; -.
DR Proteomes; UP000283993; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF2; 3-OXOADIPYL-COA_3-OXO-5,6-DEHYDROSUBERYL-COA THIOLASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000283993};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:ROO27975.1}.
FT DOMAIN 5..266
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 276..399
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT REGION 212..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 89
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 356
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 386
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 402 AA; 41451 MW; 23DB2AC7C01076B5 CRC64;
MLDAYIYDGV RTAFGRHAGA LAPVRPDDML AAVIRTLVER NPFSLGDYED VVAGCTNQAG
EDARNVARHA GLLAGLPVEV AGQTVNRLCG SGLAATVDAA RAVTVGEGKL VIAGGVESMS
RAPFVMAKAE TAYSRNMSVF DSTIGARFPN PKILAEYGSD AMPETAQNVA DDFGISREAA
DAYAAQSQAR YEAARADGFF DDEIMPLDVP QGRKQPPLTV DADEHPRPTS TADKLAKLPP
IVANGIITAG NASGVNDGAG ALIVGSRAAG EAAGLAPRAR IIAGGVVGVP PRVMGLGPIG
ACNKVLERAG LSLSDMDVIE INEAFAAQVL GCCKELGLSA DDERLNPNGG AIAVGHPLGA
SGSRLALTGL RQLERVNGRY ALISLCIGIG QGVAMLIERN PE
//
