ID   A0A423PY52_9GAMM        Unreviewed;       695 AA.
AC   A0A423PY52;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=SAOR_01530 {ECO:0000313|EMBL:ROO30511.1};
OS   Salinisphaera orenii MK-B5.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Salinisphaerales;
OC   Salinisphaeraceae; Salinisphaera.
OX   NCBI_TaxID=856730 {ECO:0000313|EMBL:ROO30511.1, ECO:0000313|Proteomes:UP000283993};
RN   [1] {ECO:0000313|EMBL:ROO30511.1, ECO:0000313|Proteomes:UP000283993}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MK-B5 {ECO:0000313|EMBL:ROO30511.1,
RC   ECO:0000313|Proteomes:UP000283993};
RA   Lai Q., Li C., Shao Z.;
RT   "Salinisphaera orenii MK-B5 Genome Sequencing.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROO30511.1}.
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DR   EMBL; AYKH01000001; ROO30511.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A423PY52; -.
DR   Proteomes; UP000283993; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF68; DNA HELICASE; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000283993}.
FT   DOMAIN          207..538
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   COILED          23..50
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   BINDING         228..235
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   695 AA;  79965 MW;  04CB48F9F698CE70 CRC64;
     MTARNTRDDD PRAEEEAHLA DIESCLQRAL RNAEDRLQRY ARDVQEQKTY LWQNRAEMDH
     VEKVNSRESI DQAVMTADKL LEHQKRLEKL RRSPYFGRFD FAVNGSETAE PVYVGIHHFH
     DEHTRRTRVY DWRAPIATLF YDYETGPARY EAPQGTIAGD IRLKRQFRIK QGRIELMIDS
     AVNVVDEVLQ DELGRTSDEG MKNIVATIQR DQNAIIRDEQ APVLIIQGVA GSGKTSIALH
     RIAFLLYRFK DTLSSEDILI ISPNRVFADY IANVLPELGE ESVNEIRMED LAEALLEGAY
     RFQSFFEQTG ALLERNDDAM RERIERKASP AFLKQLDRYA AHVERNRFVA EDVWIARRLV
     PAWLLDEIFH KHRAMGSRER IRQVVREAEQ KIGIQYNYDL TVEDRRALRT AVKGMLNETS
     LRKTYRQFYD WLGEPELFRT ASRGRLEYAD VFPLIYLKLK LESVRSPYRR VKHLLVDEMQ
     DYTPVQYAVL EKLFNCKKTV LGDVSQSINP YSASKADEIK QAFRQAVVVT LNKSYRSSYE
     ITRFAQAISP NPDLEAIERH GEAPRVIEHR RAADERAGLV AMARAFKASA RNTLGIVCKT
     QKQARRVFDT LAAAEITAQL LTEETQSFGL GIVICTAHMA KGLEFDEVIV PGADERTYHT
     AMDRKLLYVA CTRAMHRLTV TSVGPATPFV PRENC
//