ID A0A423PZG4_9GAMM Unreviewed; 423 AA.
AC A0A423PZG4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Mechanosensitive ion channel protein MscS {ECO:0008006|Google:ProtNLM};
GN ORFNames=SAJA_03915 {ECO:0000313|EMBL:ROO30986.1};
OS Salinisphaera japonica YTM-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Salinisphaerales;
OC Salinisphaeraceae; Salinisphaera.
OX NCBI_TaxID=1209778 {ECO:0000313|EMBL:ROO30986.1, ECO:0000313|Proteomes:UP000285310};
RN [1] {ECO:0000313|EMBL:ROO30986.1, ECO:0000313|Proteomes:UP000285310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YTM-1 {ECO:0000313|EMBL:ROO30986.1,
RC ECO:0000313|Proteomes:UP000285310};
RA Lai Q., Li C., Shao Z.;
RT "Salinisphaera japonica YTM-1 Genome Sequencing.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROO30986.1}.
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DR EMBL; AYKG01000008; ROO30986.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A423PZG4; -.
DR InParanoid; A0A423PZG4; -.
DR OrthoDB; 9799209at2; -.
DR Proteomes; UP000285310; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR006686; MscS_channel_CS.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS01246; UPF0003; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000285310};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 187..227
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 228..294
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 304..389
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 423 AA; 46875 MW; 1940225D540307B4 CRC64;
MRKFLGTGIT VLLFVSTVIA GCAALYSVFH PGFFGDLPAR KIAWTSLVLL GSWIISRVID
RIAVGMSRGQ RAWQKKLRNL LNVDEGEPFR EVDLTAALLH LSIWLLVPLA LLFVWGLSAQ
SFSALQHLAW SGFTFGQVQI VPAQLILGAL LLVILTALIR WVTGRMEHHW LAATPMETHT
REAVSTITGY VLFLIAALVV LSYVGLDLTK LAFIAGALSV GIGFGLQTIV NNFVSGLILL
FEQPVRRGNF VTIGETEGFV RRIRIRATEI ETLDRTTVAV PNSELLTLHL KNWNLRDRYG
RVICAVGVAY GSDVRLVERL LIDVANQNPD VLSQGQAGVP KPAALFIGFG DSTLDFELRC
FVRDVTRRYF VRSDLNFAID AAFREHDVTI AFPQMDIWHR SVPREALSVA TRNRPAADAD
ADE
//
