ID A0A423SI55_PENVA Unreviewed; 722 AA.
AC A0A423SI55;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 10.
DE SubName: Full=Alpha 2 macroglobulin {ECO:0000313|EMBL:ROT63906.1};
GN ORFNames=C7M84_018195 {ECO:0000313|EMBL:ROT63906.1};
OS Penaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC Penaeoidea; Penaeidae; Penaeus.
OX NCBI_TaxID=6689 {ECO:0000313|EMBL:ROT63906.1, ECO:0000313|Proteomes:UP000283509};
RN [1] {ECO:0000313|EMBL:ROT63906.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT63906.1};
RA Zhang X., Yuan J., Li F., Xiang J.;
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ROT63906.1, ECO:0000313|Proteomes:UP000283509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Muscle {ECO:0000313|EMBL:ROT63906.1};
RA Sun Y., Gao Y., Yu Y.;
RT "The decoding of complex shrimp genome reveals the adaptation for benthos
RT swimmer, frequently molting mechanism and breeding impact on genome.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROT63906.1}.
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DR EMBL; QCYY01003359; ROT63906.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A423SI55; -.
DR STRING; 6689.A0A423SI55; -.
DR Proteomes; UP000283509; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR CDD; cd02897; A2M_2; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR Gene3D; 2.60.40.690; Alpha-macroglobulin, receptor-binding domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR009048; A-macroglobulin_rcpt-bd.
DR InterPro; IPR036595; A-macroglobulin_rcpt-bd_sf.
DR InterPro; IPR041813; A2M_TED.
DR InterPro; IPR047565; Alpha-macroglob_thiol-ester_cl.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019742; MacrogloblnA2_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR PANTHER; PTHR11412:SF171; PREGNANCY ZONE PROTEIN-LIKE PROTEIN; 1.
DR Pfam; PF07677; A2M_recep; 1.
DR Pfam; PF07678; TED_complement; 2.
DR SMART; SM01361; A2M_recep; 1.
DR SMART; SM01419; Thiol-ester_cl; 1.
DR SUPFAM; SSF49410; Alpha-macroglobulin receptor domain; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
DR PROSITE; PS00477; ALPHA_2_MACROGLOBULIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000283509};
KW Signal {ECO:0000256|SAM:SignalP};
KW Thioester bond {ECO:0000256|ARBA:ARBA00022966}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..722
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019144846"
FT DOMAIN 622..712
FT /note="Alpha-macroglobulin receptor-binding"
FT /evidence="ECO:0000259|SMART:SM01361"
SQ SEQUENCE 722 AA; 79416 MW; F996D6A65EA2AE86 CRC64;
MRRDLCQLRV FLFLFFSCPS LRLVCLHNSP SFLILPPSSF FFSSRSPSLQ LLFCSLYQPF
FSPLGGQGRV RPPGEGRGTV RADIHHHLHA LLLGLDPPAL RQARRGPARQ PWISVFNYLD
QPLPVRVILE ESSEYEVVED PSLGTGNERT SCLAPQDKVV HTIKIQALAL GDVNLTVSAF
VDSSIPEACD TTEPVVKRDT LIKPIKVEAE GFPREETWTK YVCAEELAEG KDSMEVWQVA
PPEKIVADSA RGWVTAVGDL LALSLENLGS LIRMPYGCGE QNMINFAPNI YIMQYLEATR
QGTPETTEKL LRFMRTGYQR ELLYRRTNGS FSAFGNADDS GSTWLTAFVL KSFAQADPYI
SGGLADSGTP VPLTAYVLTA LIEAGTIPTA RIVTDATRCV LSDSSSDPYT VAVKAYALAL
AKHPEAQTLL QQLIDMAVVE ENAMYWETAT GSSKSSPLAV ETAGYAILAM MTQDPEQYVL
NARKVVKWIT TKRNGLGGFY STQDTVVALQ AMASYETNTH QGPLDVVATV TAKDFSHAFT
VNENNKLLEQ LQKLPTFPTD VTVNIEGQGC AVMQAVLRYN IPEPEASDAF ALNVTATNDP
SGGCVSKRVQ ACSSYLLPDG KSNMAVIEVN LISGFIPEKE DLKAVVKYNS KVVKRYDVDG
SKVSFYIEEF KAGEEVCVSF RISREVEIEN TKPGSVVVYD YYQPEFAVSK SYSFPAIDGC
TR
//
