ID A0A423VKX5_9PEZI Unreviewed; 687 AA.
AC A0A423VKX5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=tRNA (guanine(26)-N(2))-dimethyltransferase {ECO:0000256|ARBA:ARBA00039099};
DE EC=2.1.1.216 {ECO:0000256|ARBA:ARBA00039099};
GN ORFNames=VMCG_09263 {ECO:0000313|EMBL:ROV91666.1};
OS Valsa malicola.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Diaporthales; Valsaceae; Valsa.
OX NCBI_TaxID=356882 {ECO:0000313|EMBL:ROV91666.1, ECO:0000313|Proteomes:UP000283895};
RN [1] {ECO:0000313|EMBL:ROV91666.1, ECO:0000313|Proteomes:UP000283895}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=03-1 {ECO:0000313|EMBL:ROV91666.1,
RC ECO:0000313|Proteomes:UP000283895};
RA Yin Z., Huang L.;
RT "Host preference determinants of Valsa canker pathogens revealed by
RT comparative genomics.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Trm1 family. {ECO:0000256|PROSITE-ProRule:PRU00958}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ROV91666.1}.
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DR EMBL; LKEA01000054; ROV91666.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A423VKX5; -.
DR STRING; 356882.A0A423VKX5; -.
DR Proteomes; UP000283895; Unassembled WGS sequence.
DR GO; GO:0160102; F:tRNA (guanine(10)-N2)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.30.56.70; N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR002905; Trm1.
DR InterPro; IPR042296; tRNA_met_Trm1_C.
DR NCBIfam; TIGR00308; TRM1; 1.
DR PANTHER; PTHR10631; N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10631:SF3; TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE; 1.
DR Pfam; PF02005; TRM; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51626; SAM_MT_TRM1; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; Reference proteome {ECO:0000313|Proteomes:UP000283895};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00958};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU00958};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00958}; tRNA processing {ECO:0000256|PROSITE-ProRule:PRU00958};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555, ECO:0000256|PROSITE-
KW ProRule:PRU00958}.
FT REGION 93..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 625..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..671
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 687 AA; 75708 MW; 04D888FEB6836CEE CRC64;
MASEARGIDA TPAAGQIISL NDTRYTTIQE GRAFILVPEP SKAAADQKDI RSKDGPVQSV
FYNPIQQFNR DLTVLAIKAH GEETVERRKK AIEAKIKRNN DKKRKRQEPK AADDDSEKVA
KTHDAASPHD PQAAQGAAQA MSPEVEEAIG EVKYAIEQAA NNGTPAQQQT RPEAEDTQMQ
DAAAEGQTAQ PNESSDGQSS QVPVREIKPS FTILDALSAT GLRALRYAQE MPFVTKVTAN
DLDPSAVESI RRNIIHNKLE DKIEVTKGDA VGHMYMKIAE QMALTEKEKA QGKSGKYDVL
DLDPYGTAAT FLDAAVQSVR DDGGLLCVTC TDAGVWASNG YPEKAFALYG GIPVKGSHSH
EVGLRLILNS IATSAARYGL TIEPLLSLSI DFYARVFVRV RKSPAAVKFA AGKTMIMYNC
DTGCGAWTTQ PLLKNKSAPN KNGKGSFYKH QMTQGPTADQ HCEHCGFRTH LAGPMYAGRL
HSPDFVKRIL DKLPEADKEV YGTTERIKGM LTTALEEHLE EIGTEGRPKS KEEALAEIEP
YPFFFLPTQL ARTIHCATPG EDLLRGAIRG LGYRVTRSHC KPGSIKTDAP WSVLWEIMRE
WTRQKAPIKE DNIKPGTPGF RILGLKAKDQ PTEPKEDGAD AEGEKEEEKR AVIFDEKLGR
EKNKEKLIRY QMNPRENWGP MNRAKGQ
//
