ID   A0A423WPT5_9PEZI        Unreviewed;       607 AA.
AC   A0A423WPT5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=Vacuolar protein sorting-associated protein 17 {ECO:0000256|PIRNR:PIRNR011791};
GN   ORFNames=VSDG_00360 {ECO:0000313|EMBL:ROW05391.1};
OS   Valsa sordida.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Diaporthales; Valsaceae; Valsa.
OX   NCBI_TaxID=252740 {ECO:0000313|EMBL:ROW05391.1, ECO:0000313|Proteomes:UP000284375};
RN   [1] {ECO:0000313|EMBL:ROW05391.1, ECO:0000313|Proteomes:UP000284375}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YSFL {ECO:0000313|EMBL:ROW05391.1,
RC   ECO:0000313|Proteomes:UP000284375};
RA   Yin Z., Huang L.;
RT   "Host preference determinants of Valsa canker pathogens revealed by
RT   comparative genomics.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the membrane-associated retromer complex which
CC       is essential in endosome-to-Golgi retrograde transport.
CC       {ECO:0000256|PIRNR:PIRNR011791}.
CC   -!- SUBUNIT: Component of the retromer complex.
CC       {ECO:0000256|PIRNR:PIRNR011791}.
CC   -!- SIMILARITY: Belongs to the VPS17 family.
CC       {ECO:0000256|PIRNR:PIRNR011791}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROW05391.1}.
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DR   EMBL; LJZO01000001; ROW05391.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A423WPT5; -.
DR   STRING; 252740.A0A423WPT5; -.
DR   Proteomes; UP000284375; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0030904; C:retromer complex; IEA:InterPro.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR   CDD; cd06891; PX_Vps17p; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR014461; Retromer_complex_Vps17.
DR   InterPro; IPR037907; Vps17_PX.
DR   InterPro; IPR015404; Vps5_C.
DR   PANTHER; PTHR47433; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17; 1.
DR   PANTHER; PTHR47433:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF09325; Vps5; 1.
DR   PIRSF; PIRSF011791; Vps17; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|PIRNR:PIRNR011791};
KW   Reference proteome {ECO:0000313|Proteomes:UP000284375};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR011791}.
FT   DOMAIN          184..261
FT                   /note="PX"
FT                   /evidence="ECO:0000259|Pfam:PF00787"
FT   DOMAIN          319..498
FT                   /note="Sorting nexin/Vps5-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09325"
FT   REGION          1..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          528..607
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..33
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        80..148
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   607 AA;  66379 MW;  096E4C35D6D5B409 CRC64;
     MDYSASIQDA DHPAGASPWG TSPVSSPQAH RTTFSAVAAE PPASPTPFDS QIPRNGFGAA
     HDEGGFGAPE HGYERPGTAP SVSESDTQAH TTETAPGPGD PSAGQQQPGS SEDENVSPSR
     AHESNRLSGD TTHANQAEHQ VRKPTQPTYK LQAKITGLER AARKDPILRF DVHTNLPNFR
     TTQFRDVRRL HSEFVKLAEH LISANPEALV PAVPPPLTSA GAGTDEDEIR VKALMQRWFN
     YVCSNEVLAR DDEMVLFVES DFGYSPMIKK KQPATGVRRK LLKQFAPPPD DTPELSDARP
     VVKLFYLGSM DAGHKVDKLV KSRLGLSQSE FGVRLGGMHI QEPHQGLANA YRKLGKFVQT
     VGDSQQAQAT AEAFTIGDPF QYHSSDAFIV KETLTNRQLL IREFLQAQEN TRGKLNAADR
     LKASSNVRRE KVDEAITALD EARQSEAYLY QKTQRVTQNL VHERRKWFAR TTADLRASIR
     EFVCKEIEAE RRTLALLENV RPDVRAIDSS GGLSRLGREA HPVVRRTTLA SSQGPKGDAW
     SGVPRRTADT MGRSMSGSFM SNVGDEGDGE EEGARSPAGG LLGLGEEDDE DRVDARNAAS
     RLATSTF
//