ID   A0A423X2H7_9PEZI        Unreviewed;      1075 AA.
AC   A0A423X2H7;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Polyketide synthase phosphopantetheine-binding domain-containing protein {ECO:0000259|SMART:SM00823};
GN   ORFNames=VMCG_02037 {ECO:0000313|EMBL:ROW10094.1};
OS   Valsa malicola.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Diaporthales; Valsaceae; Valsa.
OX   NCBI_TaxID=356882 {ECO:0000313|EMBL:ROW10094.1, ECO:0000313|Proteomes:UP000283895};
RN   [1] {ECO:0000313|EMBL:ROW10094.1, ECO:0000313|Proteomes:UP000283895}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03-1 {ECO:0000313|EMBL:ROW10094.1,
RC   ECO:0000313|Proteomes:UP000283895};
RA   Yin Z., Huang L.;
RT   "Host preference determinants of Valsa canker pathogens revealed by
RT   comparative genomics.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ROW10094.1}.
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DR   EMBL; LKEA01000003; ROW10094.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A423X2H7; -.
DR   STRING; 356882.A0A423X2H7; -.
DR   Proteomes; UP000283895; Unassembled WGS sequence.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR   GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   PANTHER; PTHR43439:SF2; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR   PANTHER; PTHR43439; PHENYLACETATE-COENZYME A LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000283895}.
FT   DOMAIN          571..644
FT                   /note="Polyketide synthase phosphopantetheine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00823"
SQ   SEQUENCE   1075 AA;  117138 MW;  C9B47B7C6A71EDE7 CRC64;
     MATDLHHQGP KLWPQLVDQL ARERPNTAYG LWPVASDSYE AGFHTITYGH LANIVNGLAW
     WIVKELGAGQ GSQHEVLTYI GPNDVRLTAM ILASVKAGYA LFLTSPRNSP AAQRSLFEAL
     KCRTLVTSDS KLPPVLPILE IVKPRCLTIP TLDELLEESF PLFAYDKAFE AGRWDPLFIL
     HTSGSTGLPK PLVWTQESAV RHYASASQEV PAQQDVTSVE HLISGKRVVV TVPSFHGAGI
     LQYMVWAIRA GCIPIAPAAV GIVTAHGLAD ALKHTPAEVA ILVPSVVADL AQNPDQLAYC
     ASHLSLILYI GGDLPQAIGD VVAAKIPLRC WWGASEVGIP HQLIPRGLGP NDWRYIRFHS
     SVGAVFDPVS DGTYELVIRK DKALAQTSFS IRGQEHLAEY RTKDLFQPHP TVADAWSWRA
     RSDDIIVFLN GEKTNPVSME QHVVARNPEL SGALVIGTQR FQAALLIDPV ALNERGPLTT
     SEQAALIERV WPSVQEANAV APAHARVEKS LILVVDRPLI RAGKGTIQRA TSIQQYTSQI
     ESLYTHADVA VDDENSPDEP QVNLNDTESV TRFVRESVCA VTDWPYSHQA FSTGTFFEHG
     MDSLMALRLI RLLRRGLHRP DLGLSTIYSN PSVDQLSTAL LAQRDERKDD DALLMKPWLD
     TYRALIEQIP KPKDIHAVQK PSGASVTALL TGSTGTVGTF LLRALLDRPG IGRIYCLNRS
     EDGGYAAQKL RMTERGLSVA DLDDRVTFLP ADLSQPLLGL DEKKYKELSD HVGIIIHNAW
     PVNFNLRLSA FQPQLAGLVN LFRLSTAASS GHPASLIFVS SVSAVGTGGS AAGKRPIPEQ
     VPTLGDAPNT NGYARSKFLS ELLCDTAAQK LGIPATIARV GQVAGAVRQP GGEWNRKEWF
     PSLVIGSLSM GCLPNDLGTQ FSEIDWLPAD LLADVLVDLV QDQLSSEPEE SGSACVYNLR
     NPHTTTWESL MPSVIDAAST LLGPDRVPRV VSPSSWLEKL DDAASKETGD GAIANPAVKL
     VEFYRDYLWG EGEQGAGQDT PPMSVEKTYA HSPTLRGLQA VTAQWVQKWM GEWIS
//