ID A0A426Q5H9_9CORY Unreviewed; 403 AA.
AC A0A426Q5H9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Bifunctional RNase H/acid phosphatase {ECO:0000313|EMBL:RRQ04522.1};
GN ORFNames=CXF42_04335 {ECO:0000313|EMBL:RRQ04522.1};
OS Corynebacterium bovis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=36808 {ECO:0000313|EMBL:RRQ04522.1, ECO:0000313|Proteomes:UP000278422};
RN [1] {ECO:0000313|EMBL:RRQ04522.1, ECO:0000313|Proteomes:UP000278422}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16-2004 {ECO:0000313|EMBL:RRQ04522.1,
RC ECO:0000313|Proteomes:UP000278422};
RA Gulvik C.A.;
RT "Twenty Corynebacterium bovis Genomes.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRQ04522.1}.
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DR EMBL; PQNQ01000008; RRQ04522.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A426Q5H9; -.
DR Proteomes; UP000278422; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR CDD; cd09279; RNase_HI_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR014636; RNaseH/PGlycerate_mutase.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR48100; BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED; 1.
DR PANTHER; PTHR48100:SF1; PHOSPHOGLYCERATE MUTASE PMU1-RELATED; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR PIRSF; PIRSF036922; RNaseH_PGAM; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000278422}.
FT DOMAIN 14..154
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 144..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 207
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT ACT_SITE 284
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT BINDING 257
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ SEQUENCE 403 AA; 42440 MW; 71B08D47E01573E3 CRC64;
MTAGGQQQGT TGRVPAEVAV ECDGGSRGNP GTAGAGSLVL TADRRTVLAT CHEYIPRATN
NVAEYTGLVN ALTLARDLGA RRVHVHMDSK LVVEQMSGRW KIKHPDMKPL AATVKALEKD
FDAVDYTWVP RADNARADAL ANQAMDTKAS GEELPSGGDA AATSGTGGDA AATSGGDAAT
AAATSGDTAP SWMGDCDRPT RLLLLRHGQT ELSAEGRFSG LSDPALTATG RDQARRAAAY
LAFRGGIDAV VTSPLRRTRE TAAACVASLG LDEAAVSTDR GVVELDFGEW EGRTFAEVHE
RWADEHTAWM TDPTVPAVGG ESLNDVDDRV AAAVDGIVDR NPGRTVLVVS HVTPIKATVR
RALGASADIY RTLHLDLASL SVVEFYPDGR SVVRLVNDTH YLR
//
