ID A0A427AXP6_ENSVE Unreviewed; 85 AA.
AC A0A427AXP6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 03-MAY-2023, entry version 11.
DE RecName: Full=PHD finger protein ALFIN-LIKE {ECO:0000256|RuleBase:RU369089};
GN ORFNames=B296_00022776 {ECO:0000313|EMBL:RRT81020.1}, GW17_00007036
GN {ECO:0000313|EMBL:RWW28494.1};
OS Ensete ventricosum (Abyssinian banana) (Musa ensete).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Zingiberales; Musaceae; Ensete.
OX NCBI_TaxID=4639 {ECO:0000313|EMBL:RRT81020.1, ECO:0000313|Proteomes:UP000287651};
RN [1] {ECO:0000313|EMBL:RRT81020.1, ECO:0000313|Proteomes:UP000287651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX DOI=10.3390/agronomy4010013;
RA Harrison J., Moore K.A., Paszkiewicz K., Jones T., Grant M., Ambacheew D.,
RA Muzemil S., Studholme D.J.;
RT "A Draft Genome Sequence for Ensete ventricosum, the Drought-Tolerant Tree
RT Against Hunger.";
RL Agronomy (Basel) 4:13-33(2014).
RN [2] {ECO:0000313|EMBL:RWW28494.1, ECO:0000313|Proteomes:UP000288739}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Bedadit {ECO:0000313|Proteomes:UP000288739};
RC TISSUE=Leaf {ECO:0000313|EMBL:RWW28494.1};
RX PubMed=29896517; DOI=10.1016/j.dib.2018.03.026;
RA Yemataw Z., Muzemil S., Ambachew D., Tripathi L., Tesfaye K., Chala A.,
RA Farbos A., O'Neill P., Moore K., Grant M., Studholme D.J.;
RT "Genome sequence data from 17 accessions of Ensete ventricosum, a staple
RT food crop for millions in Ethiopia.";
RL Data Brief 18:285-293(2018).
RN [3] {ECO:0000313|EMBL:RRT81020.1}
RP NUCLEOTIDE SEQUENCE.
RA Harrison J., Moore K.A., Paszkiewicz K., Jones T., Grant M., Ambacheew D.,
RA Muzemil S., Studholme D.;
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Histone-binding component that specifically recognizes H3
CC tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription
CC start sites of virtually all active genes.
CC {ECO:0000256|RuleBase:RU369089}.
CC -!- SUBUNIT: Interacts with H3K4me3 and to a lesser extent with H3K4me2.
CC {ECO:0000256|RuleBase:RU369089}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369089}.
CC -!- DOMAIN: The PHD-type zinc finger mediates the binding to H3K4me3.
CC {ECO:0000256|RuleBase:RU369089}.
CC -!- SIMILARITY: Belongs to the Alfin family.
CC {ECO:0000256|RuleBase:RU369089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RRT81020.1}.
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DR EMBL; AMZH03001008; RRT81020.1; -; Genomic_DNA.
DR EMBL; JTFG03000469; RWW28494.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A427AXP6; -.
DR Proteomes; UP000287651; Unassembled WGS sequence.
DR Proteomes; UP000288739; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042393; F:histone binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR InterPro; IPR045104; Alfin.
DR InterPro; IPR021998; Alfin_N.
DR PANTHER; PTHR12321; CPG BINDING PROTEIN; 1.
DR PANTHER; PTHR12321:SF173; PHD FINGER PROTEIN ALFIN-LIKE 8; 1.
DR Pfam; PF12165; Alfin; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|RuleBase:RU369089};
KW Metal-binding {ECO:0000256|RuleBase:RU369089};
KW Nucleus {ECO:0000256|RuleBase:RU369089};
KW Reference proteome {ECO:0000313|Proteomes:UP000288739};
KW Transcription {ECO:0000256|RuleBase:RU369089};
KW Transcription regulation {ECO:0000256|RuleBase:RU369089};
KW Zinc {ECO:0000256|RuleBase:RU369089};
KW Zinc-finger {ECO:0000256|RuleBase:RU369089}.
FT DOMAIN 13..46
FT /note="Alfin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12165"
SQ SEQUENCE 85 AA; 9476 MW; 43573B1EAE7FD271 CRC64;
MEGGAGGCNQ RSPEEVFRDF RGRRAGIVKA LTTDVEKFYR QCDPGKVSRS WFRPLTSAYI
MELDGSAPAP FIYLVVSLKS KGRSE
//
