ID A0A427XLT4_9TREE Unreviewed; 833 AA.
AC A0A427XLT4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Cytochrome c oxidase assembly protein cox15 {ECO:0000313|EMBL:RSH79667.1};
GN Name=COX15 {ECO:0000313|EMBL:RSH79667.1};
GN ORFNames=EHS24_009319 {ECO:0000313|EMBL:RSH79667.1};
OS Apiotrichum porosum.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Trichosporonales; Trichosporonaceae; Apiotrichum.
OX NCBI_TaxID=105984 {ECO:0000313|EMBL:RSH79667.1, ECO:0000313|Proteomes:UP000279236};
RN [1] {ECO:0000313|EMBL:RSH79667.1, ECO:0000313|Proteomes:UP000279236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27194 {ECO:0000313|EMBL:RSH79667.1,
RC ECO:0000313|Proteomes:UP000279236};
RA Aliyu H., Gorte O., Ochsenreither K.;
RT "Genome sequence of Apiotrichum porosum DSM 27194.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the COX15/CtaA family.
CC {ECO:0000256|ARBA:ARBA00010773}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSH79667.1}.
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DR EMBL; RSCE01000009; RSH79667.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A427XLT4; -.
DR STRING; 105984.A0A427XLT4; -.
DR OrthoDB; 7506at2759; -.
DR Proteomes; UP000279236; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016653; F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor; IEA:InterPro.
DR GO; GO:0006784; P:heme A biosynthetic process; IEA:InterPro.
DR CDD; cd10567; SWIB-MDM2_like; 1.
DR Gene3D; 1.10.245.10; SWIB/MDM2 domain; 1.
DR HAMAP; MF_01665; HemeA_synth_type2; 1.
DR InterPro; IPR003780; COX15/CtaA_fam.
DR InterPro; IPR014876; DEK_C.
DR InterPro; IPR023754; HemeA_Synthase_type2.
DR InterPro; IPR019835; SWIB_domain.
DR InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR InterPro; IPR003121; SWIB_MDM2_domain.
DR PANTHER; PTHR23289; CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15; 1.
DR PANTHER; PTHR23289:SF2; CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG; 1.
DR Pfam; PF02628; COX15-CtaA; 1.
DR Pfam; PF08766; DEK_C; 1.
DR Pfam; PF02201; SWIB; 1.
DR SMART; SM00151; SWIB; 1.
DR SUPFAM; SSF47592; SWIB/MDM2 domain; 1.
DR PROSITE; PS51998; DEK_C; 1.
DR PROSITE; PS51925; SWIB_MDM2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000279236};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 565..622
FT /note="DEK-C"
FT /evidence="ECO:0000259|PROSITE:PS51998"
FT DOMAIN 751..828
FT /note="DM2"
FT /evidence="ECO:0000259|PROSITE:PS51925"
FT REGION 52..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 625..752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 641..659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..679
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 724..749
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 833 AA; 89659 MW; FDBBFAA871474776 CRC64;
MSGFLPPTAA LRALASTARC SRTTVLPRRA AAAPMPSRFA LRSLMTSASG LNRAAPRPTL
SMSSTAAATR PAPPSAGSFF AQSYLPYSSS RGSFFTPSRY LSTSATGVKA NAAASGSSSS
TENPDVRTIP RSLPIWLFGC SALVFGIIVI GGLTRLTESG LSITEWNPIT GIRPPITDAE
WEAEWDKYKV SPEGIMMNAN ITREEFKKIF FMEWGHRIAG RALGVLFVVP AIYYCARYKL
PRGLPTTLAA IALGIAAQGA IGWYMVASGL KQEILDNKEV PRVSQYRLAA HLSAALALYI
GMVYTAVSLR RDERLASLMR SGSEGFAKVD SLVTALNSPA VRKFRVAIGV LGAMVFVTAV
TGAFVAGLDA GLVYNEFPMM GEGIMPPVNE LLDPRYSKTA DQSDLVWRNA LENPVTAQFD
HRVMAVTTAT LLILQHLVAR RPVLRLGPNA LPRATQRWSA WTAAAALGQV ALGISTLIYL
VPIPLAAAHQ AGAAVVLTCI MGLAGSMRRP GRAVEALLGS LLATLSQQPR AKHTYHPQQH
CASSSIHPPI PQRPSASFIP SSAMSAYVVG LVPRIRQILK GSDLSTVSAK AVRKQLVTDG
EEPAAIKEYR GEIDERIGEI YEELAGGSDG ESEDENDKPL ASNSNSRAPH SSGHAPSSSQ
PEPLVERKPK PKKPASKGGD QVESDAAMAA RMQAEYDAAT RGARGSRRAA APTPKKKTKK
DKVKKRSASD VEDSDASDGK PKKKRGGGGG AFNKELILSD ALGAFLHEQR LSRPQTVKRI
WDYVKANDLQ DPSDRRFILC DAVMQTVFHT DKLHMFTMNK LLAQHFRDPD EVV
//
