ID   A0A427XRE2_9TREE        Unreviewed;       445 AA.
AC   A0A427XRE2;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein {ECO:0000259|Pfam:PF02826};
GN   ORFNames=EHS25_006905 {ECO:0000313|EMBL:RSH81373.1};
OS   Saitozyma podzolica.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Trimorphomycetaceae; Saitozyma.
OX   NCBI_TaxID=1890683 {ECO:0000313|EMBL:RSH81373.1, ECO:0000313|Proteomes:UP000279259};
RN   [1] {ECO:0000313|EMBL:RSH81373.1, ECO:0000313|Proteomes:UP000279259}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 27192 {ECO:0000313|EMBL:RSH81373.1,
RC   ECO:0000313|Proteomes:UP000279259};
RA   Aliyu H., Gorte O., Ochsenreither K.;
RT   "Genome sequence of Saitozyma podzolica DSM 27192.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSH81373.1}.
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DR   EMBL; RSCD01000031; RSH81373.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A427XRE2; -.
DR   STRING; 1890683.A0A427XRE2; -.
DR   Proteomes; UP000279259; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 4.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 3.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000279259}.
FT   DOMAIN          131..196
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
FT   DOMAIN          222..276
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
FT   DOMAIN          377..408
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
FT   REGION          353..372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        354..372
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   445 AA;  47867 MW;  66A737A42680D8EA CRC64;
     MMTTRPIRVL GVTQPLSPTS LSRLQSTFHT VHYHPSSPLP PEVFPEIEAL FLASAGADKL
     LQHPAIRECA TVAAAALGGG RTQAGGANGT ERDEGVERDI TVSTASGIHV VSIPNWVVAN
     LIGIYHQLPR MLQIAREQAR WSTGTEVSSG GTYVARSTRG RTAGMLGYGS LGRETARLLQ
     AHGMRIVAAN TSGKATPQDG YILPGTGDPT GSIPSAYYST RSPASFADFL GVCDVLVCTL
     PNTRDTAYLL DGERLALLPK DAVFINVGRG NLVRSVSLGM IGPADLCLLA MDCPARCLLP
     SRPSLLWPRL PRLPSTPSTF LTFLSAIFHR TLSLYRPSRS TSPHRTTITF SCPVPYPTSP
     PRRPPPLRPL PRHPPLLGAA LDVTDPEPLP PSHPLWTHPK CIVTPHLSGD AEGEFELATD
     VLLHNLERIA RGERPVNLVD VSRGY
//