ID A0A428J1Y7_9BACI Unreviewed; 539 AA.
AC A0A428J1Y7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:RSK25852.1};
GN ORFNames=EJF36_02505 {ECO:0000313|EMBL:RSK25852.1};
OS Bacillus sp. HMF5848.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=2495421 {ECO:0000313|EMBL:RSK25852.1, ECO:0000313|Proteomes:UP000274811};
RN [1] {ECO:0000313|EMBL:RSK25852.1, ECO:0000313|Proteomes:UP000274811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMF5848 {ECO:0000313|EMBL:RSK25852.1,
RC ECO:0000313|Proteomes:UP000274811};
RA Kang H., Kang J., Cha I., Kim H., Joh K.;
RT "Bacillus sp. HMF5848 Genome sequencing and assembly.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSK25852.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RWIV01000001; RSK25852.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A428J1Y7; -.
DR OrthoDB; 9759607at2; -.
DR Proteomes; UP000274811; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF2; GGDEF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000274811};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 317..369
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 404..539
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 539 AA; 60686 MW; 16F48E2DFB4EA9BC CRC64;
MRVFSSLRTR LSLIFAGIVI LLIFTLSYII GQRSINEVQS EIGDSLSELA YIMGENLDQY
MWSRYGEVDI LSELQELRNT QDIESIEVLL NKLKERFPAF AWVGLTDKDG LVIASTDGVL
RGVDISARPV YKEALQKTFI GDVHEAVLLA ELLPNPTGEQ MKFVDISTPL YDDNGNFTGV
LATHLSWNWV KDVEESMLNT LRNRPSIEFF IVSKKKNDVI LGPQDMIGRP LNTDSIELAK
TQKNGWTLET WDDGKQYLTG YVLTGGYKDY PGLEWTVLVR QPVEVAYAPS QELRSFFLVS
GLILVVLFAF LGWFLAGQIT RPLKNISRVA NRLRDGDIVK IPPYKGLTEI EILSDSLREL
VVQLTDTETE LEKMEDVAHR DHLTGLPNRK ALDIFIEKAI HKHNALTILY LDLDGFKEVN
DTFGHEVGDK LLIEVGSRLK ESVRNEELVA RIGGDEFVVV LTTLHDPKEN GKIVGERIIS
TINKSFNIEG NTLSLGCSVG GAIWTDDNTS ENINEVIRKA DQALYKVKRT GKNRVHFEA
//
