ID   A0A428P0G7_9HYPO        Unreviewed;       863 AA.
AC   A0A428P0G7;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Chloride channel protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CEP53_010320 {ECO:0000313|EMBL:RSL46461.1};
OS   Fusarium sp. AF-6.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex.
OX   NCBI_TaxID=1325737 {ECO:0000313|EMBL:RSL46461.1, ECO:0000313|Proteomes:UP000287544};
RN   [1] {ECO:0000313|EMBL:RSL46461.1, ECO:0000313|Proteomes:UP000287544}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL62590 {ECO:0000313|EMBL:RSL46461.1,
RC   ECO:0000313|Proteomes:UP000287544};
RA   Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA   Kasson M.;
RT   "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSL46461.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NKCJ01000286; RSL46461.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428P0G7; -.
DR   Proteomes; UP000287544; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   CDD; cd03684; ClC_3_like; 1.
DR   Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   PANTHER; PTHR45711; CHLORIDE CHANNEL PROTEIN; 1.
DR   PANTHER; PTHR45711:SF3; CLC CHANNEL; 1.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   SUPFAM; SSF81340; Clc chloride channel; 1.
PE   4: Predicted;
KW   Chloride {ECO:0000256|ARBA:ARBA00023214};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000287544};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        155..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        379..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        415..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        453..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        495..513
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        553..574
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..83
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          268..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        45..72
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        268..290
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   863 AA;  95510 MW;  86FEEC18C4D63ED0 CRC64;
     MAERGSEGSQ PPSPRSVRRP HPLSRNQSVG EPDERSPLLA TSRSRIRIAG STSGRNQNPS
     LSRDQSYTGG YHGSRHHSRH PSWGSRIIHA LSDRHESSMA ESKGTIFPDE RVWYDQFTST
     DWVHDAIADS YRVKQLRSRK DVWGRVRVIF DGAQGWILSA LSGFIVALMA YTVDVAESSV
     FDFKDGYCSR GWYLNRQRCC PDGACEDWTT WAHIMNYPFG DIWSSFIIYM VFVLILALLA
     CWMALWTKTV VPSAYHLTTL DENLAADNPQ QTYDEPSSSE SSTPQTVADS KPENPPMIYY
     SAAGSGVAEV RVILSGFVLH GFLGVRTLFI KMVALILSVA SGMSLGKEGP YVHMAACVGN
     ILCRIFSKYD QNDGKRREVI SAAAAAGVAV AFGAPLGGVL FGLEEVSYFF PAKTLFRTFF
     CCIVAALSLK FLNPYGTHKI VLFEVRYLVD WEYFELASFI FVGIIGGAVG ALFIKASKYW
     AQSFRRIKVI KKFPLLEVFL VALVTGLMSY WNGLTRLPVA ELLLNLASPC DGSDMDWEEQ
     TLCPKSIDDI PPILLHLFVA LLIKGFLTVI TFGIKVPAGI YVPSMVVGGL MGRIVGHAVQ
     WSVLRVPDWG VWGSCAFSQD GSCIQPGVYG LIAAGATMCG VTRLSVTLAV ILFELTGSLD
     YVLPFSLAIL VAKWTADAIE PNSIYDLLTS MNSYPFLDNK HKPIFTEDLA DIVPRIRRER
     LIDITNSPLV PATSLRVKLE LLHRAGELDG GLPIVRHGIL VGLIPVPDLG YALDQLVEES
     TDLCLMDRIP SIDEDTGVFD PTDFTPYIDP APVALDIKSP MDLVYELFSK LGLRYICVLK
     DGKYAGMTHK KTFVRYMREH GSE
//