ID   A0A428PHF4_9HYPO        Unreviewed;       998 AA.
AC   A0A428PHF4;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=BHLH domain-containing protein {ECO:0000259|PROSITE:PS50888};
GN   ORFNames=CEP53_008072 {ECO:0000313|EMBL:RSL52492.1};
OS   Fusarium sp. AF-6.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex.
OX   NCBI_TaxID=1325737 {ECO:0000313|EMBL:RSL52492.1, ECO:0000313|Proteomes:UP000287544};
RN   [1] {ECO:0000313|EMBL:RSL52492.1, ECO:0000313|Proteomes:UP000287544}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL62590 {ECO:0000313|EMBL:RSL52492.1,
RC   ECO:0000313|Proteomes:UP000287544};
RA   Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA   Kasson M.;
RT   "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSL52492.1}.
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DR   EMBL; NKCJ01000183; RSL52492.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428PHF4; -.
DR   STRING; 1325737.A0A428PHF4; -.
DR   Proteomes; UP000287544; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0032933; P:SREBP signaling pathway; IEA:InterPro.
DR   CDD; cd11399; bHLHzip_scHMS1_like; 1.
DR   Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR019006; Sre1_C.
DR   PANTHER; PTHR47336; TRANSCRIPTION FACTOR HMS1-RELATED; 1.
DR   PANTHER; PTHR47336:SF2; TRANSCRIPTION FACTOR HMS1-RELATED; 1.
DR   Pfam; PF09427; DUF2014; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000287544};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          240..314
FT                   /note="BHLH"
FT                   /evidence="ECO:0000259|PROSITE:PS50888"
FT   REGION          1..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          180..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          304..331
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        14..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..71
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..97
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        236..250
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   998 AA;  108603 MW;  ACE3CADC3CD737D2 CRC64;
     MHGAGPTMPS SHFSDMADHD SSNSLFGLQD PNLGFVDDGS VVKSDPSSSS LPNDSSSRRP
     QTQQQYYDAA AWQFNGTPPY DSYDPSSTAP PTQTSYRSSP WALTFGQDQQ QNLQQLPVSA
     GLDSLAATTL SPESIYAASI PSNPPLGPGN LQDPAILQPH IISHLTPALQ EKLRNIAMPP
     HLQYNSPKSA SSPDSAVGEG KAGLLSSPDP AELSSKASRK RKSSADPDEE EEDDDGNQPV
     KKTAHNMIEK RYRTNLNDKI AALRDSVPSL RIMSKSARGE DTTEDREELH GLTPAHKLNK
     ATVLSKATEY IRHLEKRNTR LLDENGAMQA RIAAFEKLFM AGAMNGAISP LQQPPTPIQY
     AQDSQQFVGS PMSATQEGGA PPAGMIQVPD DMKRIISAQM AAGQPYPVPQ QPYRGGNPAL
     IRQQQIQQQQ QMQQNRWSNA GPYFGKLMVG SLAGLMILEA VREDEVSNEK PEGRGLFAVP
     LHLLRSVASG LDINVMGYHI HTSLRIILLL GTFLWVFLPS LFAKAQQRPK KPQVGVLQAA
     PSLASPIHVR RQAWLTAIQT VWVPRHNFFL EATALILKTL KLSLRNAIGV HGYQMLTGLT
     EEQETARVKA WSIALDSQLA GGDVEINKSR LVLTLLASGT LPDSPMRLML KALHIRLLLW
     DPSQSRLHLG ASSAIAAKLA RTKWNEARQL KRLLTHLRRG SSEQHDDDLP EHLAALVEQE
     CDDVLNEDII QRAHNLAFNT ETTYNITAPM DGMDSVVDDT AIGSPLDAVA AWWSTQTLHR
     VMLATMEKDE EALLTKTDDI ELAINTAPIG STAQARAIVA RAVLIDKARG ANIAAALQSM
     GNEKVDALLS TSICIIDSSF QASTPDLRLA LRCAMAIAHL RRIECTPGTT HQGLRIIESI
     MTRGNASQMS LLGCTAALQL MEELFEHKVA AETFQSSLER LSGGLRLWMG GAPGEKCGVT
     SDVREKVVDR CLTITKSVVG MDSDTGYGSL DECEDDGC
//