ID   A0A428PRI6_9HYPO        Unreviewed;       521 AA.
AC   A0A428PRI6;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE            EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN   ORFNames=CEP54_009233 {ECO:0000313|EMBL:RSL55709.1};
OS   Fusarium duplospermum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex.
OX   NCBI_TaxID=1325734 {ECO:0000313|EMBL:RSL55709.1, ECO:0000313|Proteomes:UP000288168};
RN   [1] {ECO:0000313|EMBL:RSL55709.1, ECO:0000313|Proteomes:UP000288168}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL62584 {ECO:0000313|EMBL:RSL55709.1,
RC   ECO:0000313|Proteomes:UP000288168};
RA   Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA   Kasson M.;
RT   "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSL55709.1}.
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DR   EMBL; NKCI01000099; RSL55709.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428PRI6; -.
DR   STRING; 1325734.A0A428PRI6; -.
DR   Proteomes; UP000288168; Unassembled WGS sequence.
DR   GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:UniProtKB-EC.
DR   CDD; cd07085; ALDH_F6_MMSDH; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR010061; MeMal-semiAld_DH.
DR   NCBIfam; TIGR01722; MMSDH; 1.
DR   PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43866:SF3; METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000288168}.
FT   DOMAIN          37..499
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
SQ   SEQUENCE   521 AA;  56316 MW;  C346A7D11BB2E4D3 CRC64;
     MAQSNSIFKS FAYPGNHEKL ASLPPTQNFI DNELVTSNAT QWIDVHDPAT NELLTRVPES
     TNDELKEAVR SAKAAFPAWK KTSIIKRQQI MFRLTHLVRK HMDDLATSIV TEQGKTFADA
     KGDVLRGLQV CETACGITTQ LTGEVLEVAK DMETRSYRQP LGVVAAICPF NFPAMIPLWS
     LPIATVTGNC IIVKPSERDP GAAMMIAELC REAGFPPGVV NVIHGAKDAV NFLLDEPEIQ
     AISFVGSNKA GEYIYQRGTT NGKRVQANLG AKNHALLSPD ANKDHALDAI AGAAFGAAGQ
     RCMALSVLVM LGDAKEWLPD LVNKAKTYVA GSGFDPKSDF GPVITPQSRE RCEALITSAE
     KEGARIVLDG RGYKPEGFPN GNWVGPTIIA GVRPDMECYK EEIFGPVLLC MEEESLKDGI
     SLINANAWGN GAVIFTNSGA KASLFQQEID AGQVGINVPI PVPLPMFSFT GNKRSVAGTG
     LANFYGKDGL RFYTQWKTVT SLWRSEEAST GEKFTTITAA E
//