ID   A0A428QDJ6_9HYPO        Unreviewed;       735 AA.
AC   A0A428QDJ6;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Homeobox domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CEP53_004465 {ECO:0000313|EMBL:RSL63310.1};
OS   Fusarium sp. AF-6.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex.
OX   NCBI_TaxID=1325737 {ECO:0000313|EMBL:RSL63310.1, ECO:0000313|Proteomes:UP000287544};
RN   [1] {ECO:0000313|EMBL:RSL63310.1, ECO:0000313|Proteomes:UP000287544}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL62590 {ECO:0000313|EMBL:RSL63310.1,
RC   ECO:0000313|Proteomes:UP000287544};
RA   Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA   Kasson M.;
RT   "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSL63310.1}.
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DR   EMBL; NKCJ01000074; RSL63310.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428QDJ6; -.
DR   STRING; 1325737.A0A428QDJ6; -.
DR   Proteomes; UP000287544; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR11850:SF102; HOMEOBOX PROTEIN HOMOTHORAX; 1.
DR   PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000287544};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          55..118
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DOMAIN          250..278
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DNA_BIND        57..119
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          114..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          171..223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        189..221
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   735 AA;  83727 MW;  F36690E6D3395B22 CRC64;
     MKNLGNGFFG QEANPLNTLQ PGLQLQDTKP IESLPWSLDS TEAVQEPLLP NTNKRPPPKI
     GKRFSSESIR VLKSWLATNI QKPYPGPADV EALQRQTGLS RQQITTWLAN ARRRLKNQPD
     RPPTPLVRSS APVSINNLTS FEDMDPLQRW QNSPPEHEPA TASAIAQAMR GYQSTTYSPD
     RAFSGDSDPG RSLRSSSSAG STNASQSSSA YSHTSGTSLR SLDRIRKAIK RKRRRVPAER
     PVVSDSCHPY QCTFCTETFK TKWSWKRHEK SLHLSLERWE CAPPDMNHLQ SHNFGACHGR
     ALEERTFYRK DHLQQHLKLV HNAQYQKWPM DSWKEASEEI RSRCGFCGMV MKFWSDRVDH
     LAEHFKAGQT MVNWKGDWGF ESQMLDMVEN SMPPYLIHYE RNSPWPFTTQ QGLTGSPASA
     FELIKVELEY FNANYTNARH CPPPDEELLY ESCCIIFGAE ILYKDSSTPE PSWLRDLLMS
     SEEVVKQARI RPMKSAAKSR ITELRINGKD DIFQACPMEE RLQRYVEIPK LLALRVEDDE
     LQREACAVVQ AMNESLRNPS VMFVNFLTGL IFGSTKWLIP FRQRAGLTEE TATSMFVDTG
     VGPLVVADLV PSIEPLPLTM EHQSPPETWE MTNSSAEKLN TSGIEVPASF HLNDANCYRR
     LGRELTRFVM STMSSRNPKS HVPTDDELQH QARWIMFDDG DPWNQTPADN PNWLLQFKKD
     VGLLEEESPS QVLDE
//