ID A0A428QHP5_9HYPO Unreviewed; 1277 AA.
AC A0A428QHP5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Leptomycin B resistance protein pmd1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CEP53_003925 {ECO:0000313|EMBL:RSL64825.1};
OS Fusarium sp. AF-6.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium solani species complex.
OX NCBI_TaxID=1325737 {ECO:0000313|EMBL:RSL64825.1, ECO:0000313|Proteomes:UP000287544};
RN [1] {ECO:0000313|EMBL:RSL64825.1, ECO:0000313|Proteomes:UP000287544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL62590 {ECO:0000313|EMBL:RSL64825.1,
RC ECO:0000313|Proteomes:UP000287544};
RA Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA Kasson M.;
RT "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSL64825.1}.
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DR EMBL; NKCJ01000061; RSL64825.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A428QHP5; -.
DR STRING; 1325737.A0A428QHP5; -.
DR Proteomes; UP000287544; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18577; ABC_6TM_Pgp_ABCB1_D1_like; 1.
DR CDD; cd18578; ABC_6TM_Pgp_ABCB1_D2_like; 1.
DR CDD; cd03249; ABC_MTABC3_MDL1_MDL2; 2.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF420; ABC MULTIDRUG TRANSPORTER ATRC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000287544};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 695..719
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 739..766
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 816..836
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 842..860
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 921..945
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 957..978
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 47..338
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 374..619
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 699..986
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1022..1273
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1277 AA; 139100 MW; D53F2D752EFB746C CRC64;
MGKEETTETA SNSTERVESS DPEELSASAA YVRIFRYANF SEYSLQLIAI FAAVASGAGI
ALQNLIFGDF ITSVTKYTTG RLSPAEFRDD AAQLALYFVY LGVGRFCLSY IYNSLLTYAA
HCITRNIRRE YLSAALRQEV AFFDLGTGGS VATQATSNGR LIHGGISEKL GLTFQGLSAF
VTAFIIAFVV QWKLTLICLC IAPATLLVNG AAAGIMAGYE TEILNIHAQA NAFAEGILSS
VRTIHAFGMR GPLVSKFDQY LADAHAVGKK ISPLFGMLLS TEYCIIYLGY GLAFWQGVKM
LARGEIDEPG EIFTVLLSVI IAATNLTMLA PYSIDFTRAS TAAAKLFVLI DRNSRIDPLA
STGEQPSESI IGEVELKNIT FSYPTRPGVT VLDDFSLKIP AGKVTALVGP SGSGKSTIIG
LLERWYSPHS GSIKIDGRPI DNLNLHWLRK HVRLIQQEPV LFNGTIFENI QQGLIGTQWE
DIPRKEQEKL VHEAAAMAFA HDFISDLPNG YDTQIGQRGG LLSGGQKQRI AIARSVISQP
KVLLLDEATS ALDPYAESIV QQALDKASKG RTTIVIAHKL ATIQKADNIV VMTNGRIVEQ
GTHESLLQTD GVYSRLVKIQ DLAVDDDESA SSTDETNVAD NTREDTVKLS RTLTNHDLDQ
QGMKTGQDRD NYALHKHWGI FQVLARLVRD TPELLWPYVF TVGGCILGGA MFPGQAILLA
NVMDIFSLPG SEMEREGNFY AKMFIVLGGG CLLAYFAVGY ASNIVAQQLS HKYRKQTLDD
MLRQDLQFFD REENTTGALV SRVDSNPQSI LELMGYNVAL ILVCALNVTA CSILAIAHSW
KLGLVVVCAG LPPLVGAGYL KIRWDAKISH DISERDGASA SIASEAIAAI RTVSSLAIEE
VVLKKYSAEL DHAVADCRRP LFTMMICFAF TQAIEYWFMA LGFWYGCRLL SFDKITIYEF
FVAFLGVFFA GQSAAQLFQY STSVTKGINA ANYVFWLKRL QPTIQETDEN RNNGPSYGGA
SVDLDQVRFS YPLRPSIPVL RGINLSIKKG QFVAFVGASG CGKSTMIALL ERFYDPSTGF
INIDKSPLVS LSPRLYRQLV GLVQQEPVLF QGSIRENIAL GIDDPAVDTS PSAAASHVSD
ERIESALRAA NAWEFVCSLP EGLSTSAGSG GTQLSGGQRQ RIAIARALIR NPKILLLDEA
TSALDTKSEK VVQAALAEAA KDGDRITIAV AHRLSTVKDA DAICVFHKGK IEEMGTHEEL
IAAGGLYRKM CEAQALD
//
